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Sigma-Aldrich Artificial Saliva for Pharmaceutical Research, 200mL
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Specifications:
| Application | pharmaceutical | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Standard Solutions | Forms | Liquid |
| Product Brand | Sigma-Aldrich | Target Organism Class | Candida albicans, Escherichia Coli |
| Product Grade | Laboratory grade | ||
Artificial Saliva is a laboratory-prepared formulation designed to replicate the chemical and physical properties of natural human saliva, offering a standardized medium for pharmaceutical, pharmacokinetic, and biomedical research. Developed for in vitro and in vivo applications, this solution facilitates consistent simulation of the oral environment in drug delivery, biocompatibility testing, and oral microbiological studies.
It is particularly useful in the evaluation of denture materials, mucoadhesive formulations, and oral drug stability, providing reproducible conditions for method validation, material testing, and formulation optimization.
Key Features and Benefits
- Pharmacologically relevant formulation for simulating human saliva
- Ready-to-use – No preparation required
- Standardized composition ensures reproducibility in drug delivery and dissolution testing
- Suitable for oral microbiology and dental material assessments
- Stable formulation with refrigerated storage
Composition
- Sodium Chloride
- Potassium Chloride
- Potassium Phosphate Monobasic
- Potassium Thiocyanate
- Urea
Applications
- Drug dissolution and permeability studies
- Buccal and sublingual drug delivery assessments
- Antifungal and bacterial interaction modeling
- Compatibility and degradation testing of oral pharmaceuticals
- Dental prosthetic and oral surface material studies
Recent Application Examples:
- Studying antifungal activity of Candida albicans on printed denture resins
- Investigating E. coli inactivation in droplets under various humidity conditions
- Evaluating the stability of graphene oxide–amoxicillin delivery capsules
Specifications
| Attribute | Detail |
|---|---|
| Product Name | Artificial Saliva for Pharmaceutical Research |
| Brand | Sigma-Aldrich |
| Pack Size | 200 mL |
| SKU | SAE0149-200ML |
| Formulation Type | Liquid, ready-to-use |
| Storage Conditions | Refrigerate upon receipt |
| UNSPSC Code | 51241229 |
| NACRES | NA.25 |
| Usage | For research use only |
Sigma-Aldrich’s Artificial Saliva offers a reliable and scientifically validated substitute for natural saliva in research applications related to oral drug delivery, microbiology, and dental biomaterials. With its ready-to-use format and standardized composition, it supports consistent, reproducible outcomes in pharmaceutical R&D.