Liofilchem™ MTS™ Fluconazole FLU 0.016-256, MIC Test strips

The Liofilchem™ MTS™ Fluconazole MIC Test Strips are quantitative gradient diffusion assays designed to determine the minimum inhibitory concentration (MIC) of Fluconazole (FLU) against clinically important fungi. Each strip contains a continuous gradient of fluconazole across the range of 0.016 to 256 µg/mL, making them suitable for both susceptible and resistant isolates.

MTS™ strips provide an agar-based alternative to CLSI/EUCAST broth microdilution methods, offering high reproducibility, accuracy, and ease of use in routine clinical and research laboratories.

Key Features

• Gradient diffusion strip for Fluconazole (FLU).
• Broad MIC range: 0.016–256 µg/mL.
• Accurate and reproducible results, aligned with CLSI/EUCAST standards.
• Ideal for testing both susceptible and resistant Candida isolates.
• Simple agar-based testing format for routine labs.
• Available in 10, 30, and 100 pack sizes.
• Manufactured by Liofilchem®, ISO-certified for consistent quality.

Use Cases

1. Clinical Microbiology Laboratories
   • Antifungal susceptibility testing of Candida spp. and other pathogenic yeasts.
   • Supports treatment decisions for systemic and mucosal candidiasis.
2. Hospital Infection Control & Stewardship
   • Detects fluconazole resistance, critical in managing azole-resistant Candida infections.
   • Supports antifungal stewardship programs by ensuring correct drug selection.
3. Public Health & Epidemiological Surveillance
   • Monitoring resistance trends in Candida albicans and non-albicans Candida species.
   • Generating standardized data for regional and global resistance tracking.
4. Pharmaceutical & Academic Research
   • Comparative studies of fluconazole with other azoles (e.g., itraconazole, voriconazole).
   • Benchmark antifungal activity for drug development research.

Clinical Significance

• Fluconazole is a first-line triazole antifungal used widely in the treatment of candidiasis (oral, vaginal, systemic), cryptococcal meningitis, and other fungal infections.
• Resistance to fluconazole, particularly among Candida glabrata and Candida krusei, is a growing concern, making routine MIC testing essential.
• Determining MIC values helps clinicians:
  • Identify resistant or dose-dependent isolates.
  • Guide appropriate therapeutic decisions.
  • Improve patient outcomes by preventing treatment failure.
• These strips are also valuable in tracking resistance patterns as part of antifungal surveillance initiatives.

Ordering Information

The Liofilchem™ MTS™ Fluconazole (FLU) 0.016–256 MIC Test Strips offer a reliable, reproducible, and easy-to-use solution for determining fluconazole susceptibility in pathogenic fungi. With their broad MIC range, standardized methodology, and clinical relevance, these strips are essential tools for clinical microbiology, antifungal stewardship, epidemiological surveillance, and research laboratories.