Liofilchem® Gentamicin CN, Antimicrobial Susceptibility Discs

The Liofilchem® Gentamicin CN Antimicrobial Susceptibility Discs are high-quality paper discs impregnated with defined concentrations of Gentamicin (10 µg, 30 µg, 120 µg, and 500 µg) for antibiotic susceptibility testing (AST). These discs are specifically designed to determine bacterial sensitivity or resistance to Gentamicin, providing precise, reproducible results for clinical and research laboratories.

Key Features

1. Multiple Concentrations

• Available in 10 µg, 30 µg, 120 µg, and 500 µg formulations to suit diverse testing requirements:
  • 10 µg: Standardized for routine clinical diagnostics.
  • 30 µg: Commonly used for AST in both clinical and research applications.
  • 120 µg and 500 µg: Designed for specific high-dose therapeutic scenarios or research on high-level aminoglycoside resistance (HLAR).

2. Compliance with Global Standards

• Fully compliant with EUCAST, CLSI, and ISO standards for antimicrobial susceptibility testing.
• Ensures reliable results aligned with established interpretative criteria.

3. Effective Across a Broad Range of Bacteria

• Targets Gram-negative pathogens like:
  • Enterobacteriaceae (e.g., E. coli, Klebsiella, Enterobacter spp.).
  • Pseudomonas aeruginosa and other non-fermenting Gram-negative bacilli.
• Also applicable for testing select Gram-positive organisms.

4. Precision and Quality Assurance

• Manufactured under strict quality control conditions for consistent performance and uniform drug diffusion.
• Produces clear and measurable zones of inhibition for accurate susceptibility interpretation.

5. Easy Integration

• Compatible with standard Kirby-Bauer disc diffusion methods, making it suitable for routine use in microbiology laboratories.

6. Flexible Testing Applications

• Available in various concentrations to accommodate testing for standard therapy, resistance monitoring, and specialized research.

Applications

1. Clinical Diagnostics

• Identify Gentamicin susceptibility for guiding treatment of bacterial infections.

2. Resistance Surveillance

• Detect and monitor trends in Gentamicin resistance, including multidrug-resistant organisms.

3. High-Level Resistance Testing

• Use higher concentration discs (e.g., 120 µg, 500 µg) to investigate high-level aminoglycoside resistance (HLAR) in pathogens like Enterococcus spp.

4. Research and Development

• Evaluate the efficacy of Gentamicin in experimental settings or study resistance mechanisms.

Specifications

Advantages

1. Multiple Concentrations:
   • Enables testing across different clinical and research scenarios, including routine AST and HLAR detection.
2. Ease of Use:
   • Seamlessly integrates into existing disc diffusion workflows.
3. Standardized and Reliable:
   • Uniform drug delivery ensures reproducible results.
4. Cost-Effective:
   • Suitable for high-throughput laboratories.

How It Works

1. Inoculate Plate:
   • Spread a standardized bacterial suspension onto a Mueller-Hinton agar plate.
2. Apply Discs:
   • Place Gentamicin discs (10 µg, 30 µg, 120 µg, or 500 µg) on the agar surface.
3. Incubation:
   • Incubate at 35–37°C for 16–18 hours.
4. Result Interpretation:
   • Measure the diameter of the zone of inhibition and interpret results using established guidelines.

Why Choose Liofilchem® Gentamicin CN Discs?

• Versatility: Available in multiple concentrations for various testing needs.
• Reliability: Delivers accurate, standardized results in line with global guidelines.
• Broad Applicability: Effective against a wide range of clinically relevant bacterial pathogens.

The Liofilchem® Gentamicin CN Antimicrobial Susceptibility Discs are essential tools for precise and efficient antibiotic susceptibility testing, addressing both routine and specialized microbiology needs.