Gibco™ LV-MAX™ Production Medium

The Gibco™ LV-MAX™ Production Medium is a chemically defined, serum-free, and protein-free cell culture medium, optimized for high-density growth and transfection of Gibco Viral Production Cells (suspension-adapted HEK 293-derived cells). This medium is a key component of the LV-MAX™ Lentiviral Production System, supporting scalable, high-titer lentiviral vector production for gene therapy, viral vector manufacturing, and bioprocessing applications.

With no need for additional supplementation, this ready-to-use formulation ensures lot-to-lot consistency, high reproducibility, and maximum lentivirus yield.

Key Features & Benefits

1. High-Titer Lentiviral Production

• Enables sustained, high-yield lentivirus production in transiently transfected suspension cultures.
• Achieves lentiviral titers of up to 1 × 10⁸ TU/mL (unconcentrated LVVs-GFP).
• Specifically optimized for HEK 293-derived viral production cells.

2. Supports High-Density Cell Growth

• Cultures Viral Production Cells to densities exceeding 1 × 10⁷ cells/mL.
• Compatible with various culture formats, including 96-deep well plates, 2-L flasks, and bioreactors.
• Enables efficient scale-up for large-scale lentivirus production.

3. Chemically Defined, Serum-Free, Protein-Free Formulation

• Eliminates animal-origin components, reducing batch variability and regulatory concerns.
• No antibiotics or unnecessary additives, improving reproducibility and transfection efficiency.
• Supports consistent viral vector manufacturing with high lot-to-lot reliability.

Specifications

Available Product Variants

Applications

1. Lentiviral Vector Production for Gene Therapy & Research

• Optimized for scalable lentivirus production in suspension culture HEK 293 cells.
• Achieves high transfection efficiency using LV-MAX™ transfection reagent.

2. Cell & Gene Therapy Development

• Supports CAR-T cell engineering and other gene delivery applications.
• Enables high-yield transient lentivirus production for research and clinical development.

3. Bioprocessing & Large-Scale Virus Production

• Compatible with bioreactor workflows, facilitating large-scale lentiviral vector manufacturing.
• Ideal for high-throughput viral screening assays.

Storage & Handling

• Store at 2–8°C, protecting from direct light exposure.
• Do not freeze, as freezing may alter medium composition.
• Maintain sterile conditions when handling to prevent contamination.

Ordering Information

The Gibco™ LV-MAX™ Production Medium is a chemically defined, serum-free, and protein-free medium optimized for high-yield lentivirus production in suspension HEK 293-derived Viral Production Cells. With scalability from small-scale cultures to bioreactors, this medium is an ideal solution for gene therapy, viral vector manufacturing, and bioprocessing applications.