Apollo Sci. TCEP-HCL, 98%

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Used in the reduction of disulphide groups

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Specifications:
Application molecular biology
Storage Temperature 2-8°C
Product Type Laboratory Chemical Forms Powder
Product Brand Apollo Scientific
Product Grade Analytical grade

Apollo Scientific TCEP-HCl is a high-purity, water-soluble reducing agent widely used in biochemistry and molecular biology for reducing disulfide bonds in proteins and peptides. Known for its superior stability compared to DTT, TCEP-HCl is a reliable choice for applications requiring efficient and consistent reduction under aqueous conditions.

Key Features:

  1. High Purity:
    • 98% pure formulation ensures reliable and reproducible results.
  2. Stable and Effective:
    • More stable than DTT, TCEP-HCl does not oxidize easily, making it ideal for air-exposed workflows.
  3. Water Soluble:
    • Easily dissolves in water, simplifying preparation and application in aqueous systems.
  4. Efficient Reduction:
    • Selectively reduces disulfide bonds in proteins and peptides.

Applications:

  1. Reduction of Disulfides:
    • Ideal for reducing protein and peptide disulfide bonds in biochemical research.
  2. Sample Preparation:
    • Used in mass spectrometry workflows to prepare reduced samples.
  3. Biochemical Analysis:
    • Supports enzyme studies, protein assays, and other reduction-based applications.

Specifications:

AttributeDetails
Chemical FormulaC₉H₁₆ClO₆P
Molecular Weight286.65 g/mol
Purity98%
Melting Point177–178 °C
Water SolubilityFully soluble
StabilityMore stable than DTT
Storage TemperatureRefrigerator (2–8°C)
MDL NumberMFCD00145469
CAS Number51805-45-9
Hazard ClassificationUN 3261, ADR 8, II (Corrosive, Danger)

Advantages:

FeatureBenefit
High StabilityRemains active longer than DTT under ambient conditions.
Water SolubilitySimplifies handling and preparation.
High PurityReduces variability in experimental results.
Selective ReductionEfficiently reduces protein disulfides without side reactions.

Handling and Storage:

  • Storage Conditions: Store in a refrigerator (2–8°C) for optimal stability.
  • Safety Precautions: Classified as Corrosive; wear appropriate personal protective equipment (PPE) when handling.
  • Shipping Classification: UN 3261, ADR 8, II (corrosive).

Chemical and Physical Properties:

PropertyValue
Synonyms3,3',3''-Phosphinetriyltripropanoic acid hydrochloride, TCEP
Molecular StructureTris(2-carboxyethyl)phosphine hydrochloride
DensityNot specified
Boiling PointNot specified


For efficient and reliable reduction of disulfides in proteins and peptides, Apollo Scientific TCEP-HCl is an excellent choice for your biochemical and molecular biology needs.

  • Pack Size:   5g 10g 25g
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