Thermo Scientific™ Slide-A-Lyzer™ Dialysis Flasks

Thermo Scientific™ Slide-A-Lyzer™ Dialysis Flasks are designed to simplify the dialysis of protein and macromolecule samples in volumes up to 250 mL. These easy-to-use, high-capacity flasks feature low-protein-binding regenerated cellulose membranes and are available in multiple molecular weight cut-off (MWCO) options to suit a wide range of molecular separations. Each flask includes flotation disks for vertical suspension during dialysis, improving convenience and minimizing contamination risk.

Unlike traditional dialysis tubing, these devices require no clips, clamps, or knots—just pipette or pour your sample into the wide-mouth opening and begin dialysis.

Key Features and Benefits

Simple, Clip-Free Operation

• No tubing, knots, or clamps required—add sample directly using a pipette or by pouring.
• Wide-mouth screw cap allows easy access and complete sample recovery.

Rapid Dialysis with High Recovery

• Dual-membrane design and flat flask geometry enable fast diffusion and short dialysis times—typically 8 hours to overnight.
• High membrane surface area maximizes buffer exchange and salt removal efficiency.

Color-Coded MWCO Options

• Purple (20K MWCO), Orange (10K), Pink (3.5K), and Blue (2K) for easy identification.
• Select the MWCO best suited for your sample's molecular weight range.

Cleanroom Manufactured for Sample Purity

• Produced under cleanroom conditions and shipped with minimal glycerol and heavy metal residues.
• Low-binding cellulose membranes help maximize protein recovery and prevent sample loss.

Applications

• Buffer exchange for protein purification workflows
• Desalting of enzyme, antibody, and macromolecule preparations
• Removal of unreacted labels or small molecules post-conjugation
• Preparation of samples for downstream electrophoresis or spectrophotometry
• Sample cleanup before mass spectrometry or chromatography

Technical Specifications

Ordering Information

Slide-A-Lyzer™ Dialysis Flasks offer a modern, convenient alternative to traditional dialysis tubing for large-volume samples. Their clip-free design, broad MWCO range, and rapid dialysis performance make them ideal for protein purification, buffer exchange, and sample cleanup workflows in academic, pharmaceutical, and biotechnology laboratories.