Thermo Scientific™ Slide-A-Lyzer™ MINI Dialysis Devices, 10K MWCO

Thermo Scientific™ Slide-A-Lyzer™ MINI Dialysis Devices, 10K MWCO provide a simple, efficient, and low-loss method for dialyzing and desalting small-volume samples (10 µL to 2 mL) of proteins, nucleic acids, and other macromolecules. Each device integrates a regenerated cellulose membrane with a 10,000 Dalton molecular weight cut-off (MWCO) into a polypropylene cup that fits conveniently into standard microcentrifuge or conical tubes.

These single-use devices eliminate the need for complex setups and minimize sample loss compared to traditional filtration or resin-based purification systems. With rapid performance and >95% recovery in many cases, these dialysis units are ideal for researchers requiring fast, reliable sample processing without contamination risk.

Key Features and Benefits

Convenient Sizes for Multiple Workflows

• Available in 0.1, 0.5, and 2 mL formats, compatible with 1.5 mL microcentrifuge, 15 mL, and 50 mL conical tubes.
• No special adapters or assembly tools required.

Efficient Sample Recovery and Speed

• >95% recovery with high performance in desalting, buffer exchange, and contaminant removal.
• Typical dialysis completion in 4–8 hours, with rapid equilibration in some cases (e.g., <10 minutes for small volumes).

Ease of Use

• Pre-assembled, leak-tested devices require no additional preparation.
• Pipette-accessible design allows easy sample addition/removal using standard lab pipettes.

Sterile Manufacturing

• Produced in a HEPA-filtered cleanroom and auto-bagged to ensure contaminant-free use straight from the package.

Low-Binding, Regenerated Cellulose Membrane

• Chemically compatible with most buffers and reagents.
• Minimal protein adsorption compared to alternative dialysis or filtration systems.

Applications

• Buffer exchange for proteins, peptides, or nucleic acids
• Desalting or contaminant removal post-labeling or purification
• Equilibrium dialysis
• Protein conjugation reactions
• Concentration and cleanup of small-volume biological samples

Technical Specifications

Ordering Information

Slide-A-Lyzer™ MINI Dialysis Devices, 10K MWCO offer a fast, user-friendly, and efficient way to perform dialysis on precious small-volume samples. Designed for use in standard lab tubes and racks, these devices provide excellent sample recovery and performance while eliminating the complexity of conventional dialysis methods. Ideal for life science researchers performing buffer exchange, desalting, or protein sample preparation.