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ATCC 30221 ™ Babesia microti (Franca) Reichenow
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Specifications:
| Application | Infectious disease research, Vector-borne disease research | ||
| Storage Temperature | –80°C | ||
| Product Type | Reference Strains | Forms | Frozen |
| Product Brand | ATCC | ||
| Product Grade | BSL 2 | ||
Babesia microti ATCC 30221™ (strain Gray) is a parasitic protozoan reference strain used extensively in infectious disease and vector-borne disease research. Originally isolated from a human case of piroplasm infection in Nantucket Island, Massachusetts, this strain serves as a well-established model organism for tick-borne parasitic infections.
This organism is supplied in a frozen format and is maintained through in vivo cultivation in hamster models, making it particularly valuable for studies involving host–parasite interactions, parasitemia dynamics, and therapeutic development. As a representative agent of babesiosis, B. microti is widely used in parasitology, hematology, and zoonotic disease research.
Key Features
- Authentic Babesia microti strain Gray (ATCC 30221™)
- Clinically relevant isolate from human infection
- Established model for tick-borne parasitic diseases (babesiosis)
- Suitable for in vivo propagation in hamster hosts
- Supplied as cryopreserved (frozen) culture
- Ideal for host–pathogen interaction and parasitemia studies
- Supports infectious disease and vector-borne research applications
Applications
- Infectious disease research
- Vector-borne (tick-borne) disease studies
- Parasitology and protozoan biology
- Host–parasite interaction research
- Drug discovery and therapeutic evaluation
- Hematological parasite infection models
Technical Specifications
| Parameter | Description |
|---|---|
| Organism | Babesia microti (Franca) Reichenow |
| Catalog Number | ATCC 30221™ |
| Product Category | Protists |
| Product Type | Parasitic protozoan |
| Classification | Protozoa |
| Strain Designation | Gray |
| Isolation Source | Human infection with piroplasms |
| Geographic Origin | Nantucket Island, Massachusetts, USA |
| Product Format | Frozen |
| Storage Conditions | ≤ -80°C (short-term), liquid nitrogen vapor phase (long-term) |
| Host System | In vivo cultivation in hamster |
Handling & Storage Overview
This strain is supplied as a frozen ampoule and must be handled under strict cold-chain conditions. Upon receipt, the material should be immediately transferred to liquid nitrogen storage or maintained at -80°C for short-term holding (≤1 week).
For culture initiation, the ampoule is rapidly thawed at approximately 35°C, and the contents are aseptically inoculated into an appropriate hamster host following established in vivo propagation protocols. Routine monitoring of parasitemia levels using stained blood films is required to track infection progression and determine optimal passage timing.