Thermo Scientific™ 4-Methylumbelliferone ≥97%
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Formula: C₁₀H₈O₃
Storage Temperature: Ambient
CAS Number: 90-33-5
Specifications:
Application | molecular biology, Fluorescence-Based Assay | ||
Storage Temperature | Ambient | ||
Product Type | Laboratory Chemical, Enzymes and Substrates | Forms | Powder |
Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
Product Grade | Analytical grade | Formula | C₁₀H₈O₃ |
4-Methylumbelliferone (also known as hymecromone) is a fluorogenic substrate and coumarin derivative commonly used in biochemical assays, particularly for the detection of enzymatic activity such as β-glucuronidase, lipase, and glycosidase. With high fluorescence when excited at ~360 nm and emission at ~450 nm, it serves as a sensitive tool in fluorometric detection systems.
This compound is also utilized in clinical diagnostics, cell biology, and pharmacological research for its utility in enzyme substrate studies, inhibitor screening, and drug delivery assessments. Supplied at ≥97% purity, it appears as a white to light yellow crystalline powder and is stable under ambient storage conditions.
Key Features
- High purity: ≥97% (HPLC ≥89%)
- Fluorescent coumarin derivative
- Sensitive substrate for fluorometric enzyme assays
- Stable and easy to handle solid powder form
- Excitation/emission: ~360 nm / ~450 nm
- GHS07 (Irritant) – handle with PPE
- For research use only
Applications
- β-glucuronidase activity assays
- Detection of glycosidases, lipases, phosphatases
- Fluorometric substrate in biochemical research
- Inhibitor screening in drug discovery
- Fluorescent labeling and tracking in cell biology
- Used in clinical diagnostics and high-throughput screening
Chemical & Physical Properties
Property | Specification |
---|---|
Chemical Name | 4-Methylumbelliferone |
CAS Number | 90-33-5 |
Molecular Formula | C₁₀H₈O₃ |
Molecular Weight | 176.17 g/mol |
MDL Number | MFCD00006866 |
Merck Index | 14,4854 |
Melting Point | 186–191 °C |
Appearance | White to off-white/light yellow powder |
Water Content | ≤8% |
HPLC Purity | ≥89.0% |
Storage Temperature | Ambient |
EINECS Number | 201-986-7 |
Hazard Classification | GHS07 – Irritant |
Available Packaging
Catalog Number | Pack Type | Pack Size | |
---|---|---|---|
A10337.18 | Glass bottle (solids) | 50 g | |
A10337.30 | Glass bottle (solids) | 250 g | |
A10337.0B | Glass bottle (solids) | 1 kg |
Thermo Scientific™ 4-Methylumbelliferone, ≥97% is a highly versatile fluorogenic reagent ideal for enzyme assays, biochemical analysis, and fluorescence-based detection systems. With reliable purity and strong fluorescence performance, it is an essential compound for clinical research, diagnostics, and pharmaceutical studies.
- Pack Size: 250g 1kg 50g