Thermo Scientific™ Invitrogen™ UltraPure™ Sodium Dodecyl Sulfate (SDS)

High-Purity Anionic Detergent for Protein Denaturation and Nucleic Acid Extraction

Invitrogen™ UltraPure™ Sodium Dodecyl Sulfate (SDS) is a high-grade anionic detergent widely recognized for its effectiveness in denaturing proteins and lysing cells in molecular biology workflows. Its UltraPure™ designation ensures that it meets stringent quality standards for use in electrophoretic and genomic applications.

In SDS-PAGE, SDS binds uniformly to proteins, disrupting their secondary and tertiary structures while imparting a consistent negative charge, enabling accurate molecular weight separation. It is also a critical component in DNA and RNA extraction protocols, helping to disrupt lipid membranes and dissociate nucleic acid-protein complexes.

This powder formulation is easy to dissolve and ideal for laboratories requiring reliable and reproducible results in protein electrophoresis and genomic sample preparation.

Key Features & Benefits

• UltraPure™ Grade – High-quality SDS free from contaminants that interfere with electrophoresis or nucleic acid work
• Effective Protein Denaturant – Essential for SDS-PAGE and accurate molecular weight analysis
• Versatile Lysis Agent – Disrupts cell membranes and solubilizes proteins for genomic DNA or RNA isolation
• Convenient Format – Supplied as a 500 g powder for large-scale or routine lab use
• Stable & Easy to Store – Shelf-stable at room temperature with no refrigeration required

Applications

• Protein Electrophoresis (SDS-PAGE) – Denaturing gel electrophoresis for size-based protein separation
• DNA and RNA Extraction – Lysis of cells and dissociation of protein-nucleic acid complexes
• Cell and Tissue Lysis – Breaks down cell membranes for sample preparation
• Protein Solubilization – Useful for preparing proteins for electrophoresis or downstream analysis
• Routine Molecular Biology Workflows – Core reagent in academic, clinical, and industrial laboratories

Technical Specifications

Safety & Handling

• SDS is harmful if inhaled, ingested, or absorbed through skin
• Always use personal protective equipment (PPE) including gloves and goggles
• Handle in a well-ventilated area to minimize dust exposure
• Store in a tightly closed container in a dry, well-ventilated space
• Dispose of waste according to institutional chemical safety protocols

Invitrogen™ UltraPure™ SDS is a cornerstone reagent in molecular biology, trusted for its consistent performance in protein electrophoresis and nucleic acid preparation. With high purity, excellent solubility, and dependable results, it supports rigorous research applications where reliability and quality are paramount.