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A mucolytic agent for isolation of mycobacteria from sputum.N-Acetyl-L-cysteine is used in the liquefaction and decontamination of sputum during the preparation for recovery of mycobacterium, which is called as Petroff's method. It shows antiviral activity against the influenza A viruses. It is used in the treatment of interstitial lung disease to prevent disease progression. It is an antioxidant, dietary supplement and protects liver. Further, it forms complexes with palladium, thereby it dissolves in water and remove palladium from drugs. Further, it is used in the treatment of paracetamol overdose. In addition to this, it is involved in the treatment of autism, Alzheimer's disease, bipolar disorder, major depressive disorder, obsessive-compulsive disorder, schizophrenia, and specific drug addictions like cocaine and cannabis.

General Description

• N-Acetyl-L-cysteine (acetylcysteine) is a precursor of the antioxidant glutathione, or GSH
• N-Acetyl-L-cysteine is cytoprotective and may prevent cancer, neurodegeneration, and other disease

Application

• N-Acetyl-L-cysteine is useful for cellular redox study because of its anti-inflammatory properties
• It may also be useful for psychiatric research and the study of neurodegeneration
• It is suitable for in vivo and in vitro experiments

RUO – Research Use Only

General References:

1. Catalyzes the addition of ammonia to nitriles to form amidines in high yield: Tetrahedron Lett., 40, 7067 (1999).
2. Sun, Y.; Qi, Z.; He, Q.; Cui, D.; Qian, S.; Ji, L.; Ding, S. The effect of treadmill training and N-acetyl-l-cysteine intervention on biogenesis of cytochrome c oxidase (COX). Free Radical Biol. Med. 2015, 87, 326-335.
3. Pereira, S.; Shah, A.; Fantus, I. G.; Joseph, J. W.; Giacca, A. Effect of N-acetyl-l-cysteine on insulin resistance caused by prolonged free fatty acid elevation. J. Endocrinol. 2015, 225 (1), 1-7.