Specifications:
Application | Organic Synthesis | ||
Storage Temperature | Ambient | ||
Product Type | Laboratory Chemical | Forms | Powder |
Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
Product Grade | Analytical grade | Formula | C₁₈H₁₅P |
Thermo Scientific™ Triphenylphosphine (TPP) is a high-purity organophosphorus compound widely used as a ligand in coordination chemistry, reagent in organic synthesis, and catalyst component in metal-catalyzed transformations. Its trivalent phosphorus atom bonded to three phenyl groups makes it a versatile electron-donating ligand and a nucleophilic reagent in several important chemical reactions.
Key Features
- High Purity (≥99%) – GC purity ≥98.5% ensures consistent performance in sensitive reactions
- Reagent-Grade Solid – Supplied as white crystalline powder or flakes
- Widely Used Ligand – Popular in homogeneous catalysis, especially palladium and rhodium complexes
- Thermal Stability – High melting (78.5–81.5 °C) and boiling point (377 °C)
- Available in Scalable Pack Sizes – 25 g to 5 kg packaging for lab to industrial-scale applications
Chemical & Physical Properties
Property | Specification |
---|---|
Chemical Name | Triphenylphosphine |
CAS Number | 603-35-0 |
Formula | C₁₈H₁₅P |
Molecular Weight | 262.29 g/mol |
Appearance | White crystalline powder, crystals, or flakes |
Melting Point | 78.5–81.5 °C |
Boiling Point | 377 °C (760 mmHg) |
Density | 1.194 g/cm³ (at 20 °C) |
Flash Point | 181 °C |
Storage Temperature | Ambient |
Hazard Symbols | GHS07 (Irritant), GHS08 (Health Hazard) |
Applications
- Homogeneous Catalysis – Ligand in palladium-catalyzed reactions (e.g., Suzuki, Heck, Stille couplings)
- Wittig Reactions – Precursor for phosphonium salts used in olefination of aldehydes and ketones
- Reagent in Reductive Processes – Triphenylphosphine oxide formation in Mitsunobu reactions
- Coordination Chemistry – Forms complexes with transition metals for material and catalyst design
- Pharmaceutical Chemistry – Involved in API synthesis, drug intermediates, and chiral ligands
Ordering Information
Catalog # | Pack Size | Packaging |
---|---|---|
140420250 | 25 g | Plastic bottle |
140422500 | 250 g | Plastic bottle |
140420010 | 1 kg | Plastic bottle |
140420050 | 5 kg | Plastic drum |
Thermo Scientific™ Triphenylphosphine, 99% is a high-performance ligand and synthesis reagent that meets the needs of academic, pharmaceutical, and industrial chemists. With excellent thermal stability and reactivity, it is a fundamental component in modern organometallic and synthetic chemistry.
- Pack Size: 250g 1kg 5kg 25g