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Thermo Scientific™ Flavin adenine dinucleotide disodium salt hydrate, (max. 10% H₂O) 94% (dry weight)
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Specifications:
| Application | cell Signalling | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Enzymes and Substrates | Forms | Powder |
| Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
| Product Grade | Analytical grade | Formula | C₂₇H₃₃N₉O₁₅P₂·xH₂O |
Flavin adenine dinucleotide (FAD) is a redox-active coenzyme essential for a wide range of enzymatic reactions, particularly those involved in electron transfer and oxidative metabolism. Supplied by Thermo Scientific Chemicals at ≥94% purity (dry basis) with <10% water content (Karl Fischer), this disodium salt hydrate is suitable for biochemical, molecular, and enzymatic assays.
FAD acts as a prosthetic group for flavoproteins, serving as an electron carrier in key metabolic complexes such as succinate dehydrogenase, α-ketoglutarate dehydrogenase, and components of the pyruvate dehydrogenase complex.
Key Features
- High-purity FAD (≥94% dry wt.) with consistent activity
- Supplied as a free-flowing yellow powder
- Functions as an electron carrier in a wide range of redox enzymatic systems
- Water content controlled at <10% (K.F. titration)
- Soluble in water at concentrations up to 50 mg/mL
- Used in oxidoreductase assays, mitochondrial studies, and flavoprotein biochemistry
- Research Use Only (RUO) – not for clinical or diagnostic use
Chemical & Physical Properties
| Property | Specification |
|---|---|
| CAS Number | 1891059-93-0 |
| Chemical Formula | C₂₇H₃₁N₉Na₂O₁₅P₂ |
| Molecular Weight | 829.52 g/mol (anhydrous) |
| Form | Yellow powder |
| Purity | ≥94% (dry weight) |
| Water Content | <10.0% (Karl Fischer) |
| pH (1% in water) | 5.5 – 6.5 |
| Optical Rotation | –23.2 ± 2.3° (c = 2 in water) |
| Solubility | Soluble in water (≥50 mg/mL) |
| Storage Conditions | 4 °C; store in a sealed, dry container |
| Stability | Light and moisture-sensitive |
| MDL Number | MFCD00081365 |
Packaging Options
| Catalog No. | Quantity | Product Code |
|---|---|---|
| A14495.MC | 100 mg | A14495-MC |
| A14495.ME | 500 mg | A14495-ME |
Applications
- Cofactor in enzymatic assays involving flavoproteins
- Component of succinate dehydrogenase, α-ketoglutarate dehydrogenase, and pyruvate dehydrogenase complexes
- Study of apoptosis-inducing flavoproteins (AIF-M2, AMID)
- Research on folate/FAD-dependent tRNA methyltransferases
- Redox biology, metabolic enzyme kinetics, and electron transport studies
Handling & Storage
- Store tightly closed at 4 °C, protected from light and moisture
- Avoid exposure to oxidizing agents
- Use freshly prepared solutions when possible
- For laboratory use only; not for human or animal consumption
Supporting Literature
- Torchetti, E.M. et al. FEBS Journal, 2011, 278(22), 4434–4449.
- Hamdane, D. et al. J. Biol. Chem., 2011, 286(42), 36268–36280.
Thermo Scientific’s Flavin Adenine Dinucleotide Disodium Salt Hydrate provides a reliable, high-purity biochemical standard essential for studies involving mitochondrial function, oxidative phosphorylation, and redox enzyme pathways. Its excellent solubility, consistent purity, and functional integrity make it ideal for enzyme assays, protein cofactor loading, and redox metabolism research.
- Pack Size: 100mg 500mg