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Rapid Colorimetric Reagent for the Identification of Group A Streptococci and Enterococci
The Remel™ PYR Reagent by Thermo Scientific™ is a ready-to-use liquid reagent specifically designed for the rapid identification of Group A Streptococcus (GAS) and Enterococcus spp. through the detection of PYRase (pyrrolidonyl arylamidase) activity. Used in conjunction with PYR test formats—including paper strips, discs, and LAP discs—this reagent provides a clear red color within 1–2 minutes upon hydrolysis of L-pyrrolidonyl-β-naphthylamide (PYR), enabling fast, accurate, and reliable presumptive identification of clinically important organisms.
Key Features & Benefits
- Rapid Turnaround: Results observed in 1–2 minutes
- Clear Colorimetric Readout: Bright red color indicates a positive reaction
- Easy-to-Use: No preparation required—ready-to-use liquid format in 25 mL bottle
- High Specificity: Differentiates Streptococcus pyogenes (Group A) and Enterococcus spp.
- Broad Compatibility: Suitable for use with PYR discs, PYR paper strips, and LAP discs
- Validated Method: Cited in peer-reviewed clinical microbiology publications and protocols
Applications
- Clinical Microbiology Labs: Routine identification of GAS and enterococci from culture plates
- Hospital Diagnostics: Fast presumptive ID supports early antibiotic therapy decisions
- Microbiology Education: Enzyme-based test for bacterial identification in training labs
- Quality Control: Used for verification of known reference strains in laboratory QC programs
Specifications Table
| Attribute | Details |
|---|---|
| Product Name | PYR Reagent |
| Catalog Number | R21258 |
| Format | Liquid solution |
| Volume | 25 mL |
| Detection Method | Colorimetric (Red color = Positive) |
| Target Organisms | Streptococcus pyogenes (Group A), Enterococcus spp. |
| Chemical Composition | 0.15 g/L N,N-dimethyl-aminocinnamaldehyde |
| Compatibility | PYR disc, paper strip, and LAP disc tests |
| Storage Requirements | 2°C to 8°C (Refrigerated) |
| Shelf Life | Refer to product label or CoA |
| Intended Use | In vitro diagnostic and microbiological use |
| Unit Size | Each |
Ordering Information
| Catalog Number | Description | Pack Size |
|---|---|---|
| R21258 | PYR Reagent, 25 mL Bottle | 25 mL |
The Thermo Scientific™ Remel™ PYR Reagent is a critical reagent in the presumptive identification of Group A Streptococcus and Enterococcus spp. Its rapid enzymatic action, clear red color result, and compatibility with various PYR test formats make it an indispensable tool for laboratories needing fast, dependable differentiation of PYRase-positive bacteria.
User Guide
Rapid Colorimetric Reagent for the Identification of Group A Streptococci and Enterococci
The Remel™ PYR Reagent by Thermo Scientific™ is a ready-to-use liquid reagent specifically designed for the rapid identification of Group A Streptococcus (GAS) and Enterococcus spp. through the detection of PYRase (pyrrolidonyl arylamidase) activity. Used in conjunction with PYR test formats—including paper strips, discs, and LAP discs—this reagent provides a clear red color within 1–2 minutes upon hydrolysis of L-pyrrolidonyl-β-naphthylamide (PYR), enabling fast, accurate, and reliable presumptive identification of clinically important organisms.
Key Features & Benefits
- Rapid Turnaround: Results observed in 1–2 minutes
- Clear Colorimetric Readout: Bright red color indicates a positive reaction
- Easy-to-Use: No preparation required—ready-to-use liquid format in 25 mL bottle
- High Specificity: Differentiates Streptococcus pyogenes (Group A) and Enterococcus spp.
- Broad Compatibility: Suitable for use with PYR discs, PYR paper strips, and LAP discs
- Validated Method: Cited in peer-reviewed clinical microbiology publications and protocols
Applications
- Clinical Microbiology Labs: Routine identification of GAS and enterococci from culture plates
- Hospital Diagnostics: Fast presumptive ID supports early antibiotic therapy decisions
- Microbiology Education: Enzyme-based test for bacterial identification in training labs
- Quality Control: Used for verification of known reference strains in laboratory QC programs
Specifications Table
| Attribute | Details |
|---|---|
| Product Name | PYR Reagent |
| Catalog Number | R21258 |
| Format | Liquid solution |
| Volume | 25 mL |
| Detection Method | Colorimetric (Red color = Positive) |
| Target Organisms | Streptococcus pyogenes (Group A), Enterococcus spp. |
| Chemical Composition | 0.15 g/L N,N-dimethyl-aminocinnamaldehyde |
| Compatibility | PYR disc, paper strip, and LAP disc tests |
| Storage Requirements | 2°C to 8°C (Refrigerated) |
| Shelf Life | Refer to product label or CoA |
| Intended Use | In vitro diagnostic and microbiological use |
| Unit Size | Each |
Ordering Information
| Catalog Number | Description | Pack Size |
|---|---|---|
| R21258 | PYR Reagent, 25 mL Bottle | 25 mL |
The Thermo Scientific™ Remel™ PYR Reagent is a critical reagent in the presumptive identification of Group A Streptococcus and Enterococcus spp. Its rapid enzymatic action, clear red color result, and compatibility with various PYR test formats make it an indispensable tool for laboratories needing fast, dependable differentiation of PYRase-positive bacteria.
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