Invitrogen™ DNAZap™ PCR DNA Degradation Solutions(1 & 2), 250 mL Each

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    Specifications:
    Application PCR, Nucleic Acid Extraction
    Storage Temperature 2-8°C
    Product Type Nucleic acid controls Forms Liquid
    Product Brand Thermo Fisher Scientific™, Invitrogen
    Product Grade Molecular Biology

    Invitrogen™ DNAZap™ Solutions are a two-component, highly effective nucleic acid decontamination system engineered to eliminate DNA and RNA contamination from laboratory surfaces and equipment. When mixed, these otherwise innocuous solutions form a potent reagent capable of instantaneously degrading contaminating nucleic acids—even at levels detectable by sensitive PCR assays.

    Unlike detergents or alcohol-based cleaners that merely displace nucleic acids, DNAZap™ chemically degrades DNA and RNA to nucleotides, ensuring no amplification occurs from residual contamination. DNAZap™ is safe for use on a wide variety of surfaces and tools, making it an ideal solution for PCR workstations, pipettors, microfuge tubes, thermocyclers, and benches.

    Key Features and Benefits

    • Powerful on Contact: Begins degrading DNA and RNA immediately when applied
    • Exceeds PCR Sensitivity Thresholds: Eliminates nucleic acids down to levels undetectable by PCR
    • Two-Part System: Components are safe when separate; powerful when combined
    • True Degradation, Not Displacement: Breaks nucleic acids into nucleotides, preventing false positives
    • Non-Inhibitory: Leaves no residual inhibition of downstream enzymatic reactions after rinsing
    • Broad Compatibility: Use on plastic, metal, glass, and most lab surfaces

    Recommended Applications

    • Decontamination of PCR tubes, pipettes, and thermocyclers
    • Cleaning RNA/DNA workstations
    • Nucleic acid contamination control in molecular biology workflows
    • Surface sterilization for high-sensitivity PCR/qPCR
    • Prevention of cross-contamination in amplification reactions

    Technical Specifications

    PropertySpecification
    Product TypeDNA Decontamination Reagent
    Reagent TypeTwo-part DNA/RNA degradation solution
    FormatLiquid (Solution 1 and Solution 2)
    Quantity250 mL total
    Storage Conditions2–8 °C
    Shipping ConditionsRoom temperature
    Product LineAmbion™, DNAZap™
    Usage ClassificationFor Research Use Only
    Unit SizeEach

    How to Use DNAZap™ Solutions

    1. Apply equal amounts of Solution 1 and Solution 2 to the contaminated surface.
    2. Allow the mixture to contact the surface briefly.
    3. Rinse thoroughly with nuclease-free water or buffer.
    4. Surface is ready for sensitive molecular applications.


    Invitrogen™ DNAZap™ Solutions are a trusted choice for researchers performing ultra-sensitive nucleic acid amplification who require a truly clean environment. By completely degrading residual nucleic acids rather than displacing them, DNAZap™ helps eliminate false positives and ensures reliable PCR, qPCR, RT-PCR, and molecular assay performance across a wide range of lab conditions.

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