Liofilchem® Cefpodoxime PX, Antimicrobial Susceptibility Discs, 10 µg

Liofilchem® Cefpodoxime PX antimicrobial susceptibility discs are standardized filter paper discs impregnated with 10 µg of Cefpodoxime, a third-generation cephalosporin antibiotic. These discs are used for in vitro antimicrobial susceptibility testing (AST) of bacterial isolates using the Kirby-Bauer disk diffusion method, in accordance with Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines.

Key Features

• Pre-loaded with 10 µg of Cefpodoxime for consistent and reproducible results.
• Compatible with Kirby-Bauer disk diffusion testing on Mueller-Hinton agar.
• Regulatory-compliant with CLSI and EUCAST standards.
• Sterile and individually packaged to maintain quality and accuracy.
• Used in clinical, research, and pharmaceutical laboratories to assess bacterial resistance profiles.

Use Cases of Liofilchem® Cefpodoxime PX, 10 µg

1. Clinical Microbiology Laboratories

Application:

Hospitals and diagnostic laboratories use Cefpodoxime discs to guide effective antibiotic therapy by determining bacterial resistance.

Example:

• A patient with a urinary tract infection (UTI) submits a urine sample for culture.
• The lab isolates Escherichia coli (E. coli) from the sample.
• Cefpodoxime discs are placed on a Mueller-Hinton agar plate inoculated with the isolate.
• After incubation, the zone of inhibition around the disc is measured.
• Based on CLSI breakpoints, the pathogen is classified as susceptible, intermediate, or resistant to Cefpodoxime.
• The results help physicians decide on an effective treatment plan.

2. Pharmaceutical and Antibiotic Research

Application:

Pharmaceutical companies and research institutions use these discs to study bacterial resistance trends and evaluate new antibiotic formulations.

Example:

• A research team studies multi-drug resistant Klebsiella pneumoniae strains.
• They conduct susceptibility testing to evaluate whether Cefpodoxime remains effective.
• Comparative analysis with other cephalosporins (e.g., Cefotaxime, Ceftazidime) helps determine cross-resistance patterns.
• Data contributes to antibiotic stewardship programs and the development of new treatment guidelines.

3. Veterinary Microbiology

Application:

Veterinary diagnostic labs use Cefpodoxime discs to assess antibiotic efficacy for bacterial infections in animals.

Example:

• A dog is diagnosed with a skin infection caused by Staphylococcus pseudintermedius.
• A bacterial culture is obtained from the infected site.
• The isolate is tested with Cefpodoxime discs to determine whether oral Cefpodoxime (a common veterinary antibiotic) is an appropriate treatment.
• Based on susceptibility results, the veterinarian prescribes an effective antibiotic regimen.

4. Quality Control in Diagnostic Kit Manufacturing

Application:

Manufacturers of antimicrobial susceptibility testing kits use Liofilchem® Cefpodoxime PX discs for internal quality control and lot validation.

Example:

• A microbiology product manufacturer produces AST kits.
• To ensure batch-to-batch consistency, they use Cefpodoxime discs to test standard reference strains such as ATCC bacterial strains (e.g., E. coli ATCC 25922).
• If results fall within the expected inhibition zone range, the batch is approved for distribution.

5. Public Health and Epidemiology

Application:

Government and health organizations use Cefpodoxime susceptibility discs for monitoring antimicrobial resistance (AMR) trends in bacterial pathogens.

Example:

• A national surveillance program collects respiratory infection samples to assess antibiotic resistance in Streptococcus pneumoniae.
• Cefpodoxime susceptibility data are used to track resistance patterns over time.
• Findings influence public health policies on antibiotic prescribing practices.

Liofilchem® Cefpodoxime PX, 10 µg antimicrobial susceptibility discs are critical tools in clinical diagnostics, research, veterinary medicine, quality control, and public health surveillance. Their use in Kirby-Bauer disk diffusion tests helps laboratories determine bacterial resistance profiles, supporting effective antibiotic therapy and contributing to antimicrobial stewardship efforts.