Thermo Scientific™ Polyethylene glycol 8,000

Thermo Scientific Polyethylene Glycol 8,000 (PEG 8,000) is a high-molecular-weight polymer of ethylene glycol, widely used in industrial, pharmaceutical, and laboratory applications. Its versatile properties, including water solubility and biocompatibility, make it an essential reagent across multiple fields.

Key Properties and Specifications:

1. Chemical Composition and Structure:
   • Formula: H(OCH₂CH₂)nOH
   • Molecular Weight: ~8,000 g/mol
2. Physical Characteristics:
   • Form: White, odorless powder
   • Density: 1.125 g/cm³ (at 20°C)
   • Melting Point: 55–63°C
   • Boiling Point: ~250°C (at 1013 hPa)
   • pH (10% Solution): 5–7
3. Storage and Stability:
   • Storage Conditions: Ambient temperature in a dry, well-ventilated space.
   • Stable under recommended conditions, resistant to oxidation and degradation.
4. Compliance and Reference:
   • CAS Number: 25322-68-3
   • MDL Number: MFCD01779615
   • EINECS Number: 500-038-2
   • Merck Reference: 14,7568

Applications:

1. Pharmaceutical and Biomedical Use:
   • Drug Delivery Systems: Used as an excipient for drug solubilization and controlled release formulations.
   • Cryoprotectant: Provides protection during the freezing of biological samples.
2. Laboratory Reagent:
   • Protein Precipitation: Facilitates macromolecule precipitation for biochemical analysis.
   • Fusion and Hybridization: Utilized in cell fusion experiments and DNA hybridization procedures.
3. Industrial Applications:
   • Cosmetics: Acts as a humectant and thickening agent in personal care products.
   • Adhesives and Lubricants: Adds viscosity and stability to formulations.
4. Environmental Science:
   • Serves as a component in water-soluble lubricants and stabilizers in various environmental studies.

Advantages:

• Biocompatibility: Safe for use in pharmaceutical and cosmetic applications.
• Versatility: Soluble in water and many organic solvents.
• Stability: Resistant to temperature and chemical degradation.
• Ease of Use: Odorless and non-toxic with broad pH compatibility.

Safety and Handling:

1. General Precautions:
   • Avoid inhalation of dust and contact with skin or eyes.
   • Use in a well-ventilated area and follow standard laboratory safety practices.
2. First Aid Measures:
   • Inhalation: Move to fresh air; seek medical advice if symptoms persist.
   • Skin/Eye Contact: Rinse thoroughly with water; consult a physician if irritation occurs.
3. Storage Instructions:
   • Keep tightly closed in a dry area. Protect from excessive moisture and heat.
4. Disposal Considerations:
   • Dispose of in accordance with local environmental regulations.

Thermo Scientific Polyethylene Glycol 8,000 is a highly reliable and adaptable compound that serves a wide range of applications in research, pharmaceuticals, and industrial sectors. Its stability, biocompatibility, and ease of use make it an invaluable tool for various scientific and technical endeavors.