Thermo Scientific™ Teicoplanin ≥80% A2

Teicoplanin is a glycopeptide antibiotic primarily targeting gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and other resistant strains. It works by inhibiting bacterial cell wall synthesis, specifically binding to the D-Ala-D-Ala terminus of peptidoglycan precursors, thereby disrupting bacterial growth and survival.

Key Features:

1. Active Ingredient:
   • Teicoplanin, with ≥80% purity of the A2 component.
2. Antibacterial Spectrum:
   • Effective against gram-positive bacteria, particularly those resistant to methicillin and other beta-lactam antibiotics.
3. Physical Properties:
   • Appearance: White to off-white powder.
   • Solubility: Sparingly soluble in water.
4. Chemical Properties:
   • Formula: C₈₉H₉₉Cl₂N₉O₃₃
   • Molecular Weight: 1893.701 g/mol
5. Storage:
   • Store refrigerated at 2°C to 8°C to maintain stability and potency.
6. Applications:
   • Widely used in research on antibacterial resistance mechanisms and drug development.

Specifications:

Applications:

1. Antibacterial Research:
   • Investigate mechanisms of action and resistance against gram-positive bacteria.
   • Study alternative treatments for infections caused by MRSA, Enterococcus spp., and other resistant strains.
2. Pharmaceutical Development:
   • Development and optimization of glycopeptide-based antibiotics.
3. Microbiological Studies:
   • Evaluate the efficacy of Teicoplanin in treating gram-positive bacterial infections.
4. Clinical Relevance:
   • Model compound for research into treatments for hospital-acquired infections.

Advantages:

• High Purity: Ensures reliable results in experimental setups.
• Broad Antibacterial Spectrum: Targets a wide range of gram-positive pathogens.
• Stable Formulation: Refrigeration ensures long-term stability and activity.

Storage and Handling:

• Storage Conditions:
  • Store at 2°C to 8°C to maintain optimal activity.
• Handling Precautions:
  • Use personal protective equipment (PPE) to avoid inhalation or skin contact.
  • Keep the powder away from moisture and direct sunlight.

Safety Information:

• Warning: May cause irritation; handle with care.
• Precautions: Follow laboratory safety protocols while handling.

The Thermo Scientific Teicoplanin ≥80% A2 is a high-purity glycopeptide antibiotic widely used in antimicrobial resistance research and pharmaceutical development. Its effectiveness against methicillin-resistant gram-positive bacteria makes it a critical tool for advancing treatments for resistant infections.