Thermo Scientific™ p-Toluenesulphonic acid monohydrate ≥97%

Specifications:

p-Toluenesulphonic acid monohydrate (p-TsOH·H₂O) is a high-purity organic acid commonly used as a catalyst in organic synthesis. This monohydrate form is an efficient and cost-effective catalyst, especially for nucleophilic substitution and condensation reactions. The compound is a monoclinic crystalline solid, typically found as a white to off-white powder with a melting point range of 103–106°C.

p-Toluenesulphonic acid monohydrate is used in the synthesis of benzils, highly substituted piperidines, trisubstituted benzenes, and triazoloquinazolinone derivatives, among others. It has applications in pharmaceutical, polymer chemistry, and biochemical research due to its high reactivity and versatile catalytic properties.

Key Features:

1. High Purity (≥97%):
   • This product offers reliable and consistent quality with ≥97% purity, making it ideal for research and industrial applications.
2. Effective Catalyst:
   • Acts as a catalyst for organic reactions, such as the synthesis of benzils, trisubstituted pyrazoles, piperidines, and selenated ketene dithioacetals.
3. Versatile Applications:
   • Utilized in pharmaceutical synthesis, fine chemicals production, and as a catalyst for complex reactions in organic chemistry.
4. Corrosive:
   • Classified as GHS05 (corrosive), GHS07 (harmful), it is important to follow proper safety guidelines when handling and storing this chemical.
5. Stable and Easy to Handle:
   • p-Toluenesulphonic acid monohydrate is stable under ambient conditions and is easily handled and stored in glass bottles.

Applications:

1. Synthesis of Unsymmetrical Benzils:
   • Used in the synthesis of unsymmetrical benzils, which are intermediates in organic chemistry and pharmaceutical manufacturing.
2. Substituted Piperidines:
   • Serves as a catalyst in the synthesis of highly substituted piperidines, an important class of heterocyclic compounds.
3. Trisubstituted Benzenes:
   • Used in the trimerization of alkynes to form 1,3,5-trisubstituted benzenes, a key building block in aromatic chemistry.
4. Triazoloquinazolinone Derivatives:
   • Facilitates the synthesis of triazoloquinazolinone derivatives, important in the development of pharmaceuticals with biological activity.
5. Polymer Chemistry:
   • Involved in the synthesis of polysubstituted pyrazoles and other polymeric intermediates for specialty polymers.
6. Denitrification:
   • Used in denitrification processes, particularly in wastewater treatment to remove excess nitrate.

Packaging Options:

Storage:

• Store at ambient temperature in a cool, dry place to preserve its stability and effectiveness.

p-Toluenesulphonic Acid Monohydrate ≥97% is a high-purity reagent with a wide range of applications in organic synthesis, pharmaceutical research, and industrial processes. As an effective catalyst for various synthetic reactions, it is an essential reagent in the synthesis of aromatic compounds, heterocyclic derivatives, and polymers.