Pro-Lab Vision™ Monovalent Somatic Salmonella Antisera

Pro-Lab Vision™ Monovalent Somatic Salmonella Antisera is a series of high-quality, specific antisera designed for the serological identification of Salmonella species based on their somatic (O) antigens. Each reagent targets a specific O antigen or group factor, enabling precise serotyping of Salmonella isolates. These antisera are absorbed to minimize cross-reactions, ensuring high specificity and accuracy in identifying Salmonella serogroups and serotypes.

Key Features

1. Specific Identification:
   • Monovalent antisera allow precise detection of individual O antigens or serogroups.
   • Essential for differentiating Salmonella serotypes in complex samples.
2. High Specificity:
   • Absorbed to remove cross-reacting antibodies, minimizing false positives and enhancing accuracy.
3. Comprehensive Coverage:
   • Includes antisera for a wide range of Salmonella somatic antigens, covering all major serogroups (A, B, C, D, E, etc.) and specific factors.
4. Ready-to-Use Format:
   • Supplied in 3.0 mL dropper bottles, ensuring ease of use in busy laboratory settings.
5. Reliable Quality:
   • Manufactured under stringent quality control using reference strains, ensuring consistent and reproducible results.

Antisera Variants and Targeted Groups

Applications

1. Clinical Diagnostics

• Purpose:
  • Identifies specific Salmonella serogroups and serotypes from clinical isolates.
• Use Case:
  • Detects and differentiates Salmonella in stool, blood, and urine specimens to diagnose salmonellosis.
• Example:
  • A clinical lab identifies Salmonella Typhi by detecting Group D Factor 9 and the Vi antigen.

2. Food Safety Testing

• Purpose:
  • Ensures food safety by identifying Salmonella contamination in food products.
• Use Case:
  • Rapidly screens foodborne Salmonella serotypes, critical in food production facilities.
• Example:
  • A food testing lab identifies Group B Salmonella in contaminated poultry using antisera targeting Factor 4 and Factor 5.

3. Public Health and Epidemiology

• Purpose:
  • Tracks outbreaks and monitors Salmonella serovar distribution.
• Use Case:
  • Aids in identifying the source of contamination during Salmonella outbreaks.
• Example:
  • A public health lab identifies a rare Group E serotype during a waterborne outbreak.

4. Research and Development

• Purpose:
  • Investigates antigenic diversity and Salmonella pathogenesis.
• Use Case:
  • Used in vaccine development and molecular studies to analyze somatic antigen expression.
• Example:
  • A research lab uses Factor 13 antisera to study the pathogenic role of Group G in animal models.

Advantages

1. Precision:
   • Targeted identification of somatic antigens allows precise serotyping.
2. Broad Coverage:
   • Comprehensive range of antisera covers all major Salmonella O antigens and groups.
3. Reliability:
   • Absorbed antisera minimize cross-reactivity, ensuring consistent results.
4. Ease of Use:
   • Ready-to-use dropper bottles simplify testing workflows.
5. Versatile Applications:
   • Suitable for clinical, food safety, public health, and research applications.

How It Works

1. Sample Preparation:
   • Isolate Salmonella colonies and confirm biochemical properties.
2. Agglutination Test:
   • Place a drop of the appropriate monovalent antisera on a clean slide.
   • Add a bacterial suspension from the isolated colony.
   • Mix gently and observe for agglutination, confirming the presence of the specific antigen.

Storage and Stability

• Storage Conditions: 2–8°C.
• Shelf Life: Refer to the expiration date on the packaging.
• Stability: Ensure bottles are tightly sealed to prevent contamination and evaporation.

References

1. ISO 6579-1:2017: Detection, isolation, and identification of Salmonella.
2. Public Health England: Guidelines for Salmonella Identification.
3. Clinical and Laboratory Standards Institute (CLSI): Serotyping Methods for Enteric Pathogens.

Why Choose Pro-Lab Vision™ Monovalent Somatic Salmonella Antisera?

• Comprehensive Range: Covers all major and minor serogroups.
• High Specificity: Ensures precise and accurate serotyping.
• User-Friendly: Ready-to-use format supports efficient testing.
• Proven Quality: Manufactured under stringent controls for reliable results.