Thermo Scientific™ Multiskan SkyHigh Microplate Spectrophotometer with touchscreen, cuvette and μDrop Duo Plate

The Multiskan™ SkyHigh Microplate Spectrophotometer is a highly versatile UV/Vis microplate reader designed for diverse photometric and turbidimetric research applications, including DNA, RNA, and protein analysis. Its flexible configurations, including touchscreen control, cuvette reading, and μDrop Duo Plate compatibility, make it suitable for multi-user laboratories with varied assay requirements.

Key Features and Benefits

1. Advanced Optical System:
   • Monochromator-based for free wavelength selection between 200 nm and 1000 nm.
   • Compatible with 6-48, 96-, and 384-well microplates and cuvettes.
2. Versatile Assay Capabilities:
   • Supports endpoint, kinetic, and spectral measurements.
   • Optimized modes for absorption and turbidimetric measurements.
   • Micro-volume analysis with μDrop™ and μDrop Duo Plates.
3. Fast and Efficient Performance:
   • Full spectrum of a well measured in <10 seconds.
   • DNA spectrum measured in <3 seconds.
   • Full 96-well microplate read with one wavelength in just 6 seconds.
4. Built-in Features for Specialized Applications:
   • Onboard shaking and incubation for temperature-sensitive or cell-based assays.
   • Ready-made protocols for UV-based nucleic acid/protein quantification and colorimetric assays (touchscreen models).
5. Enhanced Connectivity:
   • Cloud-enabled via Thermo Fisher Connect or Microsoft OneDrive for secure data storage, sharing, and remote management (touchscreen models).
6. Powerful SkanIt™ Software:
   • Simplifies setup of complex assays with an intuitive interface.
   • Open license for unlimited installations across multiple devices.
   • Multi-instrument compatibility with all Thermo Scientific microplate readers.
   • Editions available for life sciences research and drug discovery (FDA 21 CFR Part 11 compliance).
7. Ease of Use:
   • Intuitive touchscreen interface with multiple language options.
   • Virtual Pipetting Tool for easy plate layout definition.
   • Access to SkanIt Cloud Library with searchable protocols and application examples.

Technical Specifications

Applications

1. Nucleic Acid Analysis:
   • UV-based quantification of DNA and RNA with high sensitivity and accuracy.
2. Protein Analysis:
   • Colorimetric protein quantification and enzymatic activity measurements.
3. Cell-Based Assays:
   • Supports temperature-controlled and kinetic studies for cellular reactions.
4. Turbidimetric Measurements:
   • Optical density measurements for bacterial growth studies and related applications.
5. Spectral Scanning:
   • Endpoint, kinetic, and spectral assays for biochemical research.

Key Advantages

• Versatility: Handles multiple plate formats, cuvettes, and micro-volume plates for diverse applications.
• Fast Performance: Quick readings for high-throughput workflows.
• User-Friendly: Touchscreen interface, intuitive software, and virtual pipetting simplify operation.
• Connectivity: Cloud-enabled for modern data management and sharing.
• Customizable: Research and compliance editions available to suit various laboratory needs.

The Multiskan SkyHigh Microplate Spectrophotometer is an ideal solution for laboratories that require precision, flexibility, and speed in their photometric analyses.

Comparison of Thermo Fisher Scientific Microplate Readers

Summary

• Multiskan™ SkyHigh: Best for laboratories needing versatile absorbance capabilities for DNA, RNA, and protein assays. Includes advanced features like cloud connectivity and μDrop plate compatibility.
• Multiskan™ FC: Ideal for routine ELISA and absorbance-based assays in a cost-effective solution.
• Varioskan™ LUX: A multimode microplate reader suited for labs with diverse, high-throughput detection needs.
• Fluoroskan™: Specializes in fluorescence-based assays with high sensitivity.
• Luminoskan™: Optimized for luminescence assays, such as ATP and reporter gene studies.

The Multiskan™ SkyHigh Microplate Spectrophotometer by Thermo Fisher Scientific is a versatile UV/Vis microplate reader designed for various photometric applications, including DNA, RNA, and protein analysis. To assist in evaluating its features relative to similar models from other manufacturers, the following table provides a comparative overview:

Summary:

• Multiskan™ SkyHigh: Offers comprehensive absorbance capabilities with cloud connectivity, making it suitable for nucleic acid and protein quantification.
• BioTek Epoch 2: Provides robust absorbance measurements with a user-friendly touchscreen and micro-volume analysis via the Take3™ Plate.
• Molecular Devices SpectraMax® i3x: Features a modular design supporting multiple detection modes, allowing for future upgrades as research needs evolve.
• BMG LABTECH CLARIOstar® Plus: Delivers high-performance multimode detection with advanced features like gas regulation and enhanced sensitivity for low-volume samples.

When selecting a microplate reader, consider the specific applications, required detection modes, throughput needs, and budget constraints to determine the most appropriate instrument for your laboratory.