Liofilchem® Cefadroxil CDX Antimicrobial Susceptibility Discs, 30 µg

Liofilchem® Cefadroxil Discs (30 µg) are high-quality antimicrobial susceptibility testing (AST) discs designed for use in the Kirby-Bauer disk diffusion method on Mueller-Hinton agar. Each disc is precisely impregnated with 30 micrograms of Cefadroxil, a first-generation cephalosporin antibiotic known for its activity against Gram-positive cocci and some Gram-negative bacilli. Manufactured under ISO 9001 and ISO 13485 quality systems, these discs ensure consistent performance for clinical diagnostics, pharmaceutical testing, and microbiological research.

Key Features

• Accurate antibiotic content: Each disc contains 30 µg of Cefadroxil for reliable and reproducible testing.
• Compliant with global standards: Supports CLSI and EUCAST guidelines for AST.
• Sterile, ready-to-use format: Available in easy-to-handle cartridges or canisters to preserve sterility and potency.
• Excellent stability: Maintains performance over extended shelf life under proper storage conditions.
• Color-coded labeling: Ensures easy identification and minimizes errors during test setup.

Applications and Use Cases

1. Clinical Microbiology

Used in hospitals and diagnostic laboratories to:

• Assess the susceptibility of Staphylococcus aureus, Streptococcus spp., and Escherichia coli.
• Aid in antibiotic selection for:
  • Skin and soft tissue infections (SSTIs)
  • Upper respiratory tract infections
  • Uncomplicated urinary tract infections

2. Pharmaceutical Quality Control

• Evaluate the antimicrobial potency of Cefadroxil-based formulations.
• Perform batch consistency checks during cephalosporin drug production and release.

3. Research and Development

• Analyze susceptibility patterns in Gram-positive clinical isolates.
• Conduct resistance surveillance studies in community-acquired pathogens.
• Explore combination effects with other antimicrobials in experimental therapies.

Use Instructions

1. Prepare Mueller-Hinton agar plates as per standard protocols.
2. Inoculate the plates with a 0.5 McFarland standardized suspension of the test organism.
3. Apply one Cefadroxil disc (30 µg) onto the inoculated agar using sterile forceps or a disc dispenser.
4. Incubate plates at 35 ± 2 °C for 16–18 hours in ambient conditions.
5. Measure the zone of inhibition in millimeters.
6. Interpret results according to CLSI or EUCAST breakpoint standards.

Storage and Shelf Life

• Storage Temperature: 2–8 °C (refrigerated)
• Shelf Life: Typically 2–3 years from the date of manufacture when stored unopened and under recommended conditions.

Liofilchem® Cefadroxil CDX Discs (30 µg) are essential for evaluating the antimicrobial activity of first-generation cephalosporins in clinical and research settings. Their precision, stability, and compliance with internationally recognized testing guidelines make them a dependable choice for routine AST. These discs support efforts in effective infection management and antibiotic stewardship by enabling accurate and consistent susceptibility profiling.