Liofilchem® Cephalexin CL Antimicrobial Susceptibility Discs, 30 µg

The Liofilchem® Cephalexin CL Antimicrobial Susceptibility Discs, 30 µg, are high-quality diagnostic tools designed for use in antimicrobial susceptibility testing (AST). These standardized discs enable reliable testing of bacterial isolates for sensitivity or resistance to Cephalexin, a first-generation cephalosporin antibiotic widely used to treat various bacterial infections. The discs are compliant with international standards, ensuring accurate and reproducible results in clinical and research laboratories.

Key Features

1. Defined Antibiotic Concentration

• Each disc contains 30 µg of Cephalexin, a standard concentration used for effective disc diffusion susceptibility testing.

2. Target Pathogens

• Suitable for testing Gram-positive and Gram-negative bacteria, including:
  • Escherichia coli
  • Klebsiella pneumoniae
  • Staphylococcus aureus (including MSSA)
  • Proteus mirabilis

3. Compliance with Global Standards

• Fully compliant with EUCAST, CLSI, and ISO guidelines for antimicrobial susceptibility testing.

4. High Sensitivity

• Produces consistent and well-defined zones of inhibition for reliable interpretation of bacterial susceptibility.

5. Easy Integration into Workflows

• Designed for use with the Kirby-Bauer disc diffusion method on Mueller-Hinton agar.

6. Quality Manufacturing

• Produced under stringent quality control to ensure uniform drug delivery, precise diffusion, and stable performance.

Applications

1. Clinical Diagnostics

• Assess bacterial susceptibility to Cephalexin for guiding treatment of:
  • Urinary tract infections (UTIs)
  • Respiratory tract infections
  • Soft tissue infections
  • Skin infections

2. Resistance Monitoring

• Detect and monitor trends in bacterial resistance to beta-lactam antibiotics, particularly in healthcare settings.

3. Routine Laboratory Testing

• Ideal for high-throughput laboratories performing routine AST on clinical isolates.

4. Research and Development

• Study the efficacy of Cephalexin against various bacterial strains or investigate resistance mechanisms.

Specifications

How It Works

1. Sample Preparation:
   • Prepare a bacterial suspension standardized to 0.5 McFarland.
2. Plate Inoculation:
   • Spread the suspension evenly over a Mueller-Hinton agar plate.
3. Disc Placement:
   • Place the Cephalexin 30 µg disc onto the agar surface.
4. Incubation:
   • Incubate at 35–37°C for 16–18 hours.
5. Result Interpretation:
   • Measure the diameter of the zone of inhibition around the disc and interpret results using standardized breakpoints.

Advantages

1. Precision

• Accurate and reliable zone diameters for interpreting bacterial susceptibility.

2. Cost-Effective

• Economical solution for high-throughput testing in clinical microbiology labs.

3. Ease of Use

• Integrates seamlessly into standard AST workflows with minimal additional preparation.

4. Broad Applicability

• Effective for a wide spectrum of Gram-positive and Gram-negative pathogens.

Limitations

• May not detect all resistance mechanisms, such as extended-spectrum beta-lactamases (ESBLs).
• Additional molecular testing may be required for detailed resistance profiling.

Why Choose Liofilchem® Cephalexin CL Antimicrobial Susceptibility Discs?

• Trusted Performance: Delivers consistent results for clinical and research applications.
• Global Compliance: Meets international AST standards for reliable testing.
• High Quality: Manufactured under strict quality control to ensure uniform performance.

The Liofilchem® Cephalexin CL Antimicrobial Susceptibility Discs, 30 µg, are indispensable tools for accurate and efficient antimicrobial susceptibility testing, supporting effective treatment decisions and resistance surveillance.