Sigma-Aldrich AmberLite™ HPR4100 Cl Anion Exchange Resin

Sigma-Aldrich AmberLite™ HPR4100 Cl is a high-performance, strongly basic Type II anion exchange resin in chloride (Cl⁻) form, designed for industrial demineralization, water purification, and separation applications. This monodispersed, gel-type resin with a styrene-divinylbenzene matrix and dimethylethanolamine functional group provides high efficiency for removing mineral acids, sulfates, chlorides, and organic anions from water and chemical solutions.

AmberLite™ HPR4100 Cl is formerly known as Dowex A2 chloride and is optimized for low-pressure liquid chromatography (LPLC), ion exchange separation, and environmental applications. This resin meets FDA Food Additive Regulation 21 CFR 173.25, making it safe for water treatment applications in the food and beverage industry.

Key Features & Benefits

1. Strongly Basic (Type II) Anion Exchange Resin
   • Efficiently removes chlorides (Cl⁻), sulfates (SO₄²⁻), and other mineral acids.
   • Well-suited for high-mineral water treatment with low silica and CO₂ (<25%).
2. High Efficiency for General Demineralization
   • Used in water softening, deionization, and industrial separation applications.
   • Meets FDA food-grade regulations for safe use in water treatment.
3. Monodispersed Bead Size for Consistent Performance
   • Uniform particle size (27-34 mesh, 440-560 μm) ensures consistent flow rates and pressure drop.
   • Improves ion exchange kinetics and resin bed performance.
4. High Moisture Content & Ion Exchange Capacity
   • Moisture content of 45-54% ensures high capacity and optimal performance.
   • Exchange capacity of 1.2 meq/mL (wetted bed volume) enables efficient anion removal.
5. Versatile for Industrial & Environmental Applications
   • Used in water deionization, wastewater treatment, and low-pressure liquid chromatography (LPLC).
   • Applicable in environmental monitoring and structural characterization of iron (Fe) in natural waters.

Product Specifications

Use Cases & Applications

1. Industrial Water Treatment & Demineralization

• Industrial & Municipal Water Purification:
  • Removes sulfates, chlorides, and organic acids from water.
  • Ideal for general deionization and water softening applications.
• Boiler Feedwater Treatment:
  • Prevents scale formation by removing anionic impurities.
  • Enhances efficiency and lifespan of industrial boilers.

2. Environmental Water Monitoring & Heavy Metal Analysis

• Iron (Fe) Characterization in Natural Waters:
  • Used in structural analysis of Fe in dilute natural waters.
  • Helps in environmental assessments and heavy metal detection.
• Wastewater Treatment & Environmental Protection:
  • Eliminates toxic anions from industrial wastewater.
  • Supports environmental compliance for safe water discharge.

3. Pharmaceutical & Bioprocessing Applications

• Purification of Pharmaceutical Ingredients:
  • Removes unwanted anions and contaminants in drug formulations.
  • Ensures high purity and stability of pharmaceutical products.
• Ion Exchange in Biochemical Research:
  • Used in separation of biomolecules in analytical and preparative chromatography.
  • Ideal for buffer preparation and ionic strength control.

4. Food & Beverage Processing

• Water Deionization for Beverage Production:
  • Ensures consistent taste and purity in bottled water and beverages.
  • Complies with FDA food additive regulations for safe processing.
• Sugar Refining & Starch Processing:
  • Removes unwanted anions affecting the quality of food ingredients.
  • Improves clarity and stability of syrups and processed food products.

5. Chemical Processing & Catalysis

• Ion Exchange for Organic Synthesis:
  • Supports catalytic reactions requiring anion exchange functionality.
  • Used in polymerization and chemical synthesis applications.
• pH Adjustment in Industrial Chemical Processes:
  • Maintains optimal reaction conditions by controlling ionic balance.
  • Ensures stable production in chemical and petrochemical industries.

Regeneration & Maintenance

• Regenerate using NaCl (sodium chloride) or NaOH (sodium hydroxide) solution.
• Flush with deionized water after regeneration to remove excess chloride.
• Store in a moist condition to maintain exchange capacity and resin integrity.

Storage & Handling Instructions

• Storage Conditions:
  • Keep in a sealed container at room temperature (15-25°C).
  • Store in a cool, dry environment away from direct sunlight.
• Handling Precautions:
  • Use protective gloves, eyewear, and lab coats during handling.
  • Ensure proper ventilation when working with large resin volumes.
• Disposal Guidelines:
  • Follow local environmental regulations for industrial waste disposal.
  • Spent resin can be regenerated or safely disposed of as non-hazardous waste.

Why Choose Sigma-Aldrich AmberLite™ HPR4100 Cl?

✅ High-capacity anion exchange resin for industrial and laboratory applications

✅ Monodispersed resin beads for consistent performance and flow rates

✅ Efficient removal of chlorides, sulfates, and organic acids from water

✅ Regenerable for cost-effective and long-term operation

✅ FDA-compliant for safe use in food and beverage processing

AmberLite™ HPR4100 Cl is a premium anion exchange resin designed for high-efficiency deionization, water purification, and industrial separation, making it a versatile solution for multiple industries.