Thermo Scientific™ Vanquish™ Quaternary Serial Dual-Piston Pump F
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Max. Flow Rate: 8 mL/min.
Pressure Range: 2 to 103 MPa
Solvent Degassing: Built-in, 4 Channels
Temperature Range: 5°C to 35°C
Specifications:
| Application | HPLC | Warranty | 1 Year |
| Storage Temperature | Ambient | ||
| Product Type | Analytical Instrument | ||
| Product Brand | Thermo Fisher Scientific™ | ||
| Product Grade | Analytical grade | ||
The Thermo Scientific™ Vanquish™ Quaternary Pump F is an advanced, high-performance UHPLC pump engineered to deliver exceptional solvent blending flexibility, outstanding flow precision, and robust gradient reproducibility across complex chromatographic workflows. Designed for seamless integration into the Vanquish UHPLC platform, this pump enables the use of up to four solvents in a single method, providing unmatched versatility for method development, method transfer, and multi-solvent application switching.
Built with SmartFlow™ pumping technology, the Quaternary Pump F delivers consistent and accurate gradients independent of solvent compressibility, eluent composition, or backpressure—ensuring superior retention-time precision and high confidence in analytical results even during complex ternary and quaternary gradients.
Key Performance Features
1. Flexible Quaternary Solvent Blending
- Supports four separate solvents for advanced chromatographic method development
- Ideal for ternary and quaternary gradient applications
- Enables rapid method switching for multi-analyte workflows
- Enhances method transfer capabilities across different chromatographic systems
2. SmartFlow™ Technology for Unmatched Precision
- Automatically compensates for changes in solvent compressibility
- Delivers excellent flow and gradient precision, independent of composition
- Maintains stable retention times across UHPLC pressure ranges up to 1034 bar (15,000 psi)
- Ensures consistently accurate and reproducible analytical results
3. High-Pressure, High-Performance Pumping
- Flow rate: up to 8 mL/min
- Pressure range: 2–103 MPa (up to 1000 bar)
- Dual-piston serial design ensures pulsation-free, smooth solvent delivery
- Suitable for both UHPLC and traditional HPLC methodologies
4. Built-In 4-Channel Solvent Degassing
- Integrated degasser on all four solvent lines
- Improves baseline stability and reduces noise
- Enhances detector sensitivity and method reproducibility
5. Biocompatible Flow Path (Yes)
- Metal-free solvent path (PEEK/Titanium) for biological, peptide, protein, and metal-sensitive analytes
- Prevents sample adsorption and metal interactions
- Ideal for LC-MS, biopharma, and trace-analysis workflows
6. Viper™ Fingertight Fittings for Easy Installation
- Leak-free, torque-controlled fittings
- Tool-free installation
- Minimize dead volume and ensure optimal chromatographic efficiency
- Reduces maintenance and downtime
Applications
- Method development and optimization
- Multi-solvent UHPLC workflows
- Pharmaceutical QC and R&D
- Gradient screening applications
- Food and environmental analysis
- Biopharmaceutical characterization
- Compatibility with bio-sensitive analytes
- LC–MS workflows requiring high solvent flexibility
Specifications
| Parameter | Details |
|---|---|
| Description | Vanquish Quaternary Pump F |
| Catalog Number | VF-P20-A |
| Pump Type | Quaternary Serial Dual-Piston Pump |
| Biocompatible Version | Yes |
| Pressure Range | 2–103 MPa (1000 bar) |
| Max Flow Rate | 8 mL/min |
| Gradient Formation | Low-pressure gradient proportioning |
| Flow Accuracy | ±0.1% |
| Flow Precision | <0.05% RSD or <0.01 min SD |
| Solvent Degassing | Built-in, 4-channel |
| Temperature Range | 5–35 °C |
| Dimensions (H × W × D) | 192 × 420 × 620 mm |
| Weight | 17 kg (37 lb) |
| Power Requirements | Standard Vanquish module power |
| Unit Size | Each |
The Thermo Scientific™ Vanquish™ Quaternary Pump F provides flexible four-solvent blending, SmartFlow™ precision, biocompatible flow paths, and high-pressure UHPLC performance up to 1000 bar. Ideal for method development, multi-solvent workflows, and high-confidence gradient control.
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