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Thermo Scientific™ Dextran sulphate sodium salt, M.W. ∼ 6,500 - 10,000
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CAS Number :
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Specifications:
| Storage Temperature | 2-8°C | ||
| Product Type | Laboratory Chemical | Forms | Powder |
| Product Brand | Thermo Fisher Scientific™ | ||
| Product Grade | Analytical grade | Formula | (C₆H₇Na₃O₁₄S₃)n |
Thermo Fisher Scientific™ Dextran Sulfate Sodium (DSS) Salt is a high-purity polyanionic sulfated polysaccharide derived from dextran via esterification with chlorosulfonic acid. It is widely used in biomedical and clinical research due to its unique chemical properties, making it an essential reagent for inducing colitis models (Inflammatory Bowel Disease, IBD) in animal studies and antiviral research.
DSS is highly soluble in water and salt solutions, forming a stable, clear solution. The sulfur content of 16-20% corresponds to approximately 1.9 sulfate groups per glucosyl residue, providing strong polyanionic characteristics.
Key Features & Benefits
✅ Molecular Weight Range: 6,500 - 10,000 Da
✅ Proven Colitis-Inducing Agent – Widely used for Inflammatory Bowel Disease (IBD) research
✅ Polyanionic Properties – Essential for biomedical, virology, and immunology research
✅ High Sulfur Content (16-20%) – Ensures strong anionic interactions for research applications
✅ Freely Soluble – Forms a clear to slightly hazy solution in water and saline
✅ Validated for Research – Used in over 3,000 scientific studies
Applications
🔬 Inflammatory Bowel Disease (IBD) & Colitis Research – DSS is a key reagent in animal models for colitis and colitis-associated cancer
🦠 Antiviral Research – Used in studies involving virus interactions and inhibition mechanisms
🧬 Biomedical & Clinical Research – Investigates polyanionic interactions in molecular biology and drug development
🛠️ Viscosity & Charge Studies – Characterization of polyelectrolytes in biochemical research
Product Specifications
| Attribute | Details |
|---|---|
| Chemical Name | Dextran Sulfate Sodium (DSS) |
| Synonyms | Dextran Sulfate Sodium from Dextran |
| Molecular Formula | (C₆H₇Na₃O₁₄S₃)n |
| CAS Number | 9011-18-1 |
| MDL Number | MFCD00081551 |
| Appearance | White to light yellow or light brown powder |
| Solubility (10% in water) | Clear to slightly hazy, colorless to light yellow |
| Molecular Weight Range | 6,500 - 10,000 Da |
| Loss on Drying | ≤10% |
| Residue After Ignition | 35% - 50% |
| pH (1% solution) | 5.0 - 8.0 |
| Specific Optical Rotation | +75° to +105° (20°C, 589 nm, 6% in water) |
| Specific Viscosity | 0.018 to 0.032 (1.0M in NaCl, 25°C) |
| Sulfur Content (S) | 16 - 20% |
Catalog Numbers & Packaging Options
| Pack Type | Quantity | Catalog Number |
|---|---|---|
| Glass Bottle | 5 g | 441490050 |
| Plastic Bottle | 25 g | 441490250 |
| Plastic Bottle | 100 g | 441491000 |
Usage Guidelines
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Colitis Induction in Animal Models:
- DSS is administered via drinking water to induce chronic colitis in mice and rats.
- The severity of colitis is dose-dependent, requiring optimized concentrations for specific study designs.
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Antiviral & Molecular Biology Studies:
- DSS is used to analyze polyanionic interactions with proteins, viruses, and membranes.
- Prepare solutions using sterile water or phosphate-buffered saline (PBS) for controlled applications.
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Solution Preparation:
- Dissolve DSS in water or saline at the required concentration.
- Store prepared solutions at 4°C and avoid prolonged storage to prevent degradation.
Storage & Handling
- Storage Temperature: Refrigerator (2-8°C)
- Shipping Conditions: Ambient
- Shelf Life: Stable under recommended storage conditions
⚠️ Safety Information:
- For Research Use Only. Not for human or veterinary use.
- Use appropriate personal protective equipment (PPE) when handling.
- Refer to the Safety Data Sheet (SDS) for detailed handling guidelines.
Why Choose Thermo Fisher Scientific™ DSS Salt?
🔹 High Purity & Proven Efficacy – Consistently used in IBD and colitis research models
🔹 Validated Molecular Weight Range (6,500 - 10,000 Da) – Ensures reproducibility in experiments
🔹 Ideal for In Vivo & In Vitro Studies – Supports multiple research applications
🔹 Reliable Performance & Stability – Manufactured under strict quality control
For bulk orders, technical inquiries, or purchasing information, contact LabMart Limited today.
- Pack Size: 100g 5g 25g