Thermo Scientific™ β-Nicotinamide adenine dinucleotide hydrate 98+% (β-NAD)

Specifications:

Description:

β-Nicotinamide Adenine Dinucleotide Hydrate (β-NAD) is an essential coenzyme involved in oxidation-reduction reactions. It plays a critical role in cellular metabolism, particularly in energy production through processes like glycolysis, citric acid cycle, and oxidative phosphorylation. β-NAD is also involved in DNA repair, cell signaling, and enzyme regulation, making it an indispensable compound in biological research and biochemistry.

This high-purity form of β-NAD (98+%) is ideal for applications requiring reliable coenzyme activity, such as in enzyme assays, cellular studies, and biochemical research.

Key Features:

• High Purity: The product is 98+% pure, as verified by UV spectrophotometry, ensuring reliable results in sensitive assays.
• Stable and Soluble: The compound is highly soluble in water (1% in water), forming a clear colorless solution that is easy to incorporate into various experimental protocols.
• High Molar Absorption Coefficient: The molar absorption coefficient of ≥17000 l/(mol·cm) at λ max 260 nm, pH 7.5, provides excellent UV visibility, useful in quantitative measurements and analytical applications.

Applications:

1. Cellular Metabolism:
   • β-NAD is vital in metabolic pathways such as the citric acid cycle and oxidative phosphorylation, making it essential for studies in energy production and ATP synthesis.
2. Enzyme Assays:
   • Used in assays that involve redox reactions, such as those measuring dehydrogenase activity and other oxidoreductases.
3. Biochemical Research:
   • Important for studying DNA repair mechanisms and cell signaling, particularly in research related to aging, cancer, and neurodegenerative diseases.
4. Pharmacology:
   • Employed in drug discovery processes, particularly in the development of NAD+ dependent enzymes or therapeutic agents targeting NAD+ metabolism.

Packaging Options:

Storage:

• Store in a freezer to maintain stability and prevent degradation. This compound should be protected from moisture and light to maintain its effectiveness.

Safety and Handling:

• Handling: Use appropriate protective gloves, goggles, and lab coats when handling the substance to avoid direct contact.
• Environmental Hazard: Follow safety guidelines for disposal and handling to minimize environmental impact.

β-Nicotinamide Adenine Dinucleotide Hydrate 98+% is a high-purity, essential reagent for biochemical research, enzyme assays, and metabolism studies. Its role in oxidation-reduction reactions and cellular processes makes it a key component in molecular biology, pharmacology, and clinical research.