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ROMIL-UpS™ Methanol Ultra LC-MS is an ultra-high purity solvent specifically developed for LC-MS, UHPLC, and critical gradient HPLC applications. Manufactured under ROMIL’s stringent UpS™ (Ultra Purity Solvents) protocols, this methanol grade delivers exceptionally low UV absorbance, ultra-low residue, minimal baseline drift, and extremely low ionic and fluorescent impurities.
Its proven LC-MS suitability and outstanding chromatographic performance make it ideal for high-sensitivity, trace-level analysis, where solvent purity is essential for accurate and reproducible results.
Key Features
- Ultra LC-MS Grade – Designed for the most demanding analytical workflows
- Excellent UV Transparency – Suitable for low-wavelength detection
- Ultra-Low Residue & Impurity Levels – Enhanced sensitivity and reproducibility
- LC-MS Compatible – Passes suitability testing
- Outstanding Gradient Performance – Minimal noise and baseline drift
- Extremely Low Ionic & Fluorescent Contaminants
Analytical Specifications
General Purity
| Parameter | Specification |
|---|---|
| Assay | >99.9% |
| Water | <0.02% |
| Residue after Evaporation | <0.0001% |
| Acidity | <0.0003 meq/g |
| Alkalinity | <0.0002 meq/g |
UV Transparency
| Wavelength | Transmission |
|---|---|
| 205 nm | >10% |
| 210 nm | >50% |
| 225 nm | >80% |
| 240 nm | >95% |
| 265–400 nm | >99% |
Gradient & Baseline Performance
| Test | Specification |
|---|---|
| Gradient Use Test (230 nm) | <0.002 AU |
| Gradient Use Test (254 nm) | <0.002 AU |
| Baseline Drift @ 230 nm | <0.02 AU |
Fluorescence Impurities (as Quinine)
| Wavelength | Specification |
|---|---|
| 254 nm | <1 ppb |
| 365 nm | <1 ppb |
Trace Ionic Impurities
| Element | Limit |
|---|---|
| Ag, Cu, Fe, K, Mg, Mn, Ni, Pb, Zn | <10 ppb each |
| Al, Ca | <25 ppb each |
| Na | <50 ppb |
LC-MS Compatibility
- Suitability for LC-MS: Passes test
Applications
- Liquid chromatography–mass spectrometry (LC-MS / LC-MS/MS)
- Ultra-high-performance liquid chromatography (UHPLC)
- Critical gradient HPLC applications
- Trace-level impurity analysis
- Pharmaceutical, environmental, and research laboratories
Available Pack Sizes
| Pack Size | Product Code |
|---|---|
| 1 L | H411M |
| 2.5 L | H411L |
ROMIL-UpS™ Methanol Ultra LC-MS is a premium-grade analytical solvent engineered for laboratories that demand maximum sensitivity, consistency, and analytical confidence. With exceptional UV transparency, ultra-low impurity levels, and verified LC-MS performance, it is an ideal choice for critical gradient HPLC, UHPLC, and advanced mass spectrometry workflows.
Flyer
ROMIL-UpS™ Methanol Ultra LC-MS is an ultra-high purity solvent specifically developed for LC-MS, UHPLC, and critical gradient HPLC applications. Manufactured under ROMIL’s stringent UpS™ (Ultra Purity Solvents) protocols, this methanol grade delivers exceptionally low UV absorbance, ultra-low residue, minimal baseline drift, and extremely low ionic and fluorescent impurities.
Its proven LC-MS suitability and outstanding chromatographic performance make it ideal for high-sensitivity, trace-level analysis, where solvent purity is essential for accurate and reproducible results.
Key Features
- Ultra LC-MS Grade – Designed for the most demanding analytical workflows
- Excellent UV Transparency – Suitable for low-wavelength detection
- Ultra-Low Residue & Impurity Levels – Enhanced sensitivity and reproducibility
- LC-MS Compatible – Passes suitability testing
- Outstanding Gradient Performance – Minimal noise and baseline drift
- Extremely Low Ionic & Fluorescent Contaminants
Analytical Specifications
General Purity
| Parameter | Specification |
|---|---|
| Assay | >99.9% |
| Water | <0.02% |
| Residue after Evaporation | <0.0001% |
| Acidity | <0.0003 meq/g |
| Alkalinity | <0.0002 meq/g |
UV Transparency
| Wavelength | Transmission |
|---|---|
| 205 nm | >10% |
| 210 nm | >50% |
| 225 nm | >80% |
| 240 nm | >95% |
| 265–400 nm | >99% |
Gradient & Baseline Performance
| Test | Specification |
|---|---|
| Gradient Use Test (230 nm) | <0.002 AU |
| Gradient Use Test (254 nm) | <0.002 AU |
| Baseline Drift @ 230 nm | <0.02 AU |
Fluorescence Impurities (as Quinine)
| Wavelength | Specification |
|---|---|
| 254 nm | <1 ppb |
| 365 nm | <1 ppb |
Trace Ionic Impurities
| Element | Limit |
|---|---|
| Ag, Cu, Fe, K, Mg, Mn, Ni, Pb, Zn | <10 ppb each |
| Al, Ca | <25 ppb each |
| Na | <50 ppb |
LC-MS Compatibility
- Suitability for LC-MS: Passes test
Applications
- Liquid chromatography–mass spectrometry (LC-MS / LC-MS/MS)
- Ultra-high-performance liquid chromatography (UHPLC)
- Critical gradient HPLC applications
- Trace-level impurity analysis
- Pharmaceutical, environmental, and research laboratories
Available Pack Sizes
| Pack Size | Product Code |
|---|---|
| 1 L | H411M |
| 2.5 L | H411L |
ROMIL-UpS™ Methanol Ultra LC-MS is a premium-grade analytical solvent engineered for laboratories that demand maximum sensitivity, consistency, and analytical confidence. With exceptional UV transparency, ultra-low impurity levels, and verified LC-MS performance, it is an ideal choice for critical gradient HPLC, UHPLC, and advanced mass spectrometry workflows.
Flyer
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Spécifications
| Pack Size | Glass bottle, 1L, Glass bottle, 2.5L |