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Thermo Scientific™ Remel™ Cryptococcus Antigen Test Kit, 50 Tests
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Specifications:
| Application | Serology | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Agglutination Test Kit | Forms | Kit with Various components |
| Product Brand | Thermo Fisher Scientific™, Remel | Target Organism Class | Cryptococcus neoformans |
| Product Grade | Microbiology grade | ||
Rapid Latex Agglutination Test for Detection of Cryptococcus neoformans Antigen in Serum and CSF
The Thermo Scientific™ Remel™ Cryptococcus Antigen Latex Test Kit is a rapid, sensitive, and semi-quantitative assay for the detection of capsular polysaccharide (CPS) antigens of Cryptococcus neoformans directly from serum or cerebrospinal fluid (CSF). Designed for use in clinical laboratories, this latex agglutination test enables early diagnosis of cryptococcosis, a potentially life-threatening systemic fungal infection, particularly in immunocompromised patients.
Key Features
- Rapid Results: Obtain definitive results in 5 minutes, facilitating timely clinical decision-making
- High Sensitivity: Detects even low levels of C. neoformans antigen in serum or CSF
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Clear Interpretation:
- Positive: Agglutination or clumping visible after the rotation step
- Negative: No agglutination observed
- Semi-Quantitative Capability: Provides titers based on last positive dilution
- Monoclonal Antibody Specificity: Uses murine IgM monoclonal antibodies for improved specificity
- False-Positive Reduction: Incorporates protease treatment to eliminate rheumatoid factor interference—no need for companion latex control tests
- Diagnostic & Prognostic Use: Antigen levels correlate with disease severity and treatment response
Intended Use
A latex agglutination test for the detection of Cryptococcus neoformans antigens directly from serum or cerebrospinal fluid (CSF). For professional use in diagnostic microbiology laboratories.
Kit Contents
- Test latex (sensitized with IgM monoclonal antibody)
- Negative control
- Positive control
- Low positive control
- Protease tablet
- 10× specimen diluent
- Reaction cards
- Dispensing pipettes
Applications
- Clinical Microbiology: Diagnosis of cryptococcal meningitis or disseminated cryptococcosis
- Infectious Disease Testing: Rapid screening for cryptococcal infections in HIV/AIDS or immunocompromised patients
- Neurological Diagnostics: Detecting C. neoformans in CSF from patients with CNS symptoms
- Monitoring and Prognostics: Tracking antigen titers over time to assess therapeutic response
Specifications Table
| Parameter | Details |
|---|---|
| Product Name | Cryptococcus Antigen Latex Test Kit |
| Catalog Number | R30851501 |
| Test Format | Latex agglutination |
| Sample Types | Serum, CSF |
| Detectable Analyte | Cryptococcus neoformans antigen (CPS) |
| Time to Result | ~5 minutes |
| Quantity per Kit | 50 Tests |
| Unit Size | Each |
| Included Components | Test latex, controls, protease, diluent, accessories |
| Regulatory Status | For in vitro diagnostic use (check local availability) |
Ordering Information
- Catalog Number: R30851501
- Kit Size: 50 Tests/Kit
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Sample Types: Human serum and cerebrospinal fluid (CSF)
The Thermo Scientific™ Remel™ Cryptococcus Antigen Latex Test Kit provides a rapid, accurate, and reliable method for detecting Cryptococcus neoformans antigens in serum and CSF. With strong diagnostic and prognostic value, it is an essential tool for microbiology laboratories managing immunocompromised patients and suspected fungal meningitis cases.