Liofilchem™ MTS™ Amikacin AK 0.016-256, MIC Test strips

The Liofilchem™ MTS™ Amikacin AK MIC Test Strips are gradient diffusion tools specifically designed for the quantitative determination of the Minimum Inhibitory Concentration (MIC) of Amikacin, an aminoglycoside antibiotic. These strips offer a reliable method to test bacterial susceptibility, ensuring accurate results for clinical diagnostics and antimicrobial resistance studies.

Key Features

1. Broad MIC Range

• Covers an extensive concentration range of 0.016 to 256 μg/mL, making it suitable for detecting both low- and high-level resistance.

2. Gradient Diffusion Technology

• Each strip contains a stable gradient of Amikacin.
• Provides precise MIC values directly on an agar plate, eliminating the need for labor-intensive broth dilution methods.

3. High Sensitivity and Specificity

• Effectively detects Amikacin resistance in Gram-negative bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter spp..

4. Visual MIC Interpretation

• The intersection point between the bacterial inhibition ellipse and the strip gradient scale indicates the exact MIC value.
• Simplifies result interpretation for laboratory personnel.

5. Compliance with Global Standards

• Fully compatible with EUCAST, CLSI, and other global antimicrobial susceptibility testing guidelines.
• Ensures standardized and reproducible results.

6. Rapid and Reliable

• Delivers MIC results within 16–24 hours of incubation at 35–37°C, enabling timely clinical decisions.

7. Versatility

• Suitable for both clinical diagnostics and research laboratories, including antimicrobial resistance surveillance and pharmaceutical studies.

8. Long Shelf Life

• Manufactured to ensure stability under recommended storage conditions (2–8°C), supporting consistent performance.

Applications

1. Clinical Diagnostics:
   • Evaluate the susceptibility of Gram-negative pathogens to Amikacin for effective treatment planning.
2. Antimicrobial Resistance Monitoring:
   • Identify resistant strains of bacteria, including multidrug-resistant organisms.
3. Pharmaceutical Research:
   • Assess the efficacy of Amikacin in experimental studies.
4. Surveillance:
   • Track trends in antibiotic resistance for public health and hospital infection control.

How It Works

1. Sample Preparation:
   • Prepare bacterial suspensions following standardized protocols (e.g., McFarland standard).
2. Application:
   • Place the MTS strip on an inoculated agar plate.
3. Incubation:
   • Incubate the plate at 35–37°C for 16–24 hours under appropriate conditions.
4. Result Interpretation:
   • Read the MIC value at the point where the growth inhibition ellipse intersects the strip gradient.

Specifications

Advantages

1. Time-Saving:
   • Reduces turnaround time for MIC results compared to conventional methods.
2. Ease of Use:
   • Intuitive workflow suitable for laboratory personnel with minimal training.
3. Precise Results:
   • Gradient diffusion provides accurate and reproducible MIC values.
4. Wide Application:
   • Effective against a broad spectrum of clinically significant bacteria.

Limitations

• Further molecular testing may be required for confirming resistance mechanisms.
• Not suitable for detecting Amikacin resistance in fastidious or anaerobic bacteria without protocol adjustments.

Why Choose Liofilchem™ MTS™ Amikacin AK?

• Reliable: Provides consistent, high-quality results for clinical and research needs.
• Efficient: Combines simplicity with advanced technology to streamline antimicrobial susceptibility testing.
• Comprehensive: Covers a wide range of pathogens and resistance levels, supporting robust diagnostic workflows.

The Liofilchem™ MTS™ Amikacin AK MIC Test Strips are indispensable for clinical laboratories and research settings, offering a precise, efficient, and standardized method for determining bacterial susceptibility to Amikacin.