Gibco™ AlbuMAX™ I Lipid-Rich BSA

Gibco™ AlbuMAX™ I Lipid-Rich BSA is a highly purified, lipid-enriched bovine serum albumin (BSA) formulated for advanced cell culture applications. This product is specifically designed for serum-free and low-serum media systems to support the growth, viability, and productivity of mammalian cell lines, particularly in applications that require lipid supplementation.

Key Features

1. Lipid-Enriched Formulation:
   • Fortified with cholesterol and fatty acids, supporting cell lines with high lipid requirements.
2. High Purity:
   • Free of impurities and contaminants, ensuring optimal cell performance and minimal variability in experiments.
3. Serum-Free Compatibility:
   • Ideal for serum-free or low-serum culture systems, providing a consistent and defined environment for cell growth.
4. Enhanced Cell Viability:
   • Improves the growth and viability of hybridomas, CHO cells, HEK293 cells, and other mammalian cell lines.
5. Batch-to-Batch Consistency:
   • Manufactured under stringent quality controls for reproducible results in research and production workflows.

Applications

1. Cell Culture:
   • Supports cell proliferation and viability in serum-free and low-serum environments.
2. Hybridoma Culture:
   • Enhances antibody production in hybridoma cell lines.
3. Protein Expression:
   • Promotes recombinant protein production in CHO and HEK293 cells.
4. Virus Production:
   • Aids in the production of viruses for research and vaccine development.
5. Cryopreservation:
   • Protects cells during freezing and thawing when used in cryopreservation media.
6. Nutrient Supplementation:
   • Provides critical lipids and nutrients to enhance metabolic activity in demanding culture conditions.

Specifications

• Type: Lipid-rich bovine serum albumin (BSA)
• Form: Powder
• Purity: ≥99% with lipid supplementation
• Solubility: Soluble in aqueous solutions
• Grade: Cell culture grade
• Storage: Store at 2–8°C in a dry, tightly sealed container.

Preparation and Usage

1. Reconstitution:
   • Dissolve in sterile water or culture medium at a desired concentration (typically 0.1–5% w/v).
2. Sterile Filtration:
   • Filter the solution through a 0.2 µm filter to ensure sterility for aseptic applications.
3. Integration:
   • Add to cell culture media formulations for use in serum-free or low-serum environments.

Benefits

1. Reduced Serum Dependency:
   • Provides a defined and consistent alternative to fetal bovine serum (FBS).
2. Improved Productivity:
   • Supports high cell densities and enhances protein and antibody production.
3. Scalable:
   • Suitable for research, pilot-scale, and large-scale production workflows.

Safety and Handling

• For Research Use Only: Not intended for therapeutic or diagnostic use in humans or animals.
• Protective Equipment: Wear gloves, a lab coat, and safety goggles while handling the product.
• Disposal: Dispose of unused product and containers in accordance with local regulations.

Gibco™ AlbuMAX™ I Lipid-Rich BSA is a trusted supplement for serum-free and low-serum cell culture applications, providing essential lipids and nutrients to enhance cell growth and productivity while maintaining experimental consistency. Let me know if further details are needed!

Comparison of Gibco™ AlbuMAX™ I and AlbuMAX™ II

AlbuMAX™ I and AlbuMAX™ II are lipid-rich bovine serum albumin (BSA) products from Gibco™, designed for use in serum-free and low-serum cell culture applications. While they share similar core functions, they differ in lipid content, specific applications, and optimization for cell types.

Key Differences

Key Similarities

1. Lipid-Rich BSA:
   • Both products are lipid-enriched to support cell metabolism and growth in serum-free or low-serum conditions.
2. High Purity:
   • Both are highly purified, with minimal impurities, ensuring reproducibility in experimental workflows.
3. Applications:
   • Both are effective in cell culture, protein expression, hybridoma growth, and cryopreservation.
4. Batch Consistency:
   • Both products are manufactured under strict quality controls for consistent performance.
5. Format:
   • Supplied as powders, easily soluble in aqueous solutions.

Usage Recommendations

• Choose AlbuMAX™ I:
  • For general cell culture applications requiring moderate lipid supplementation.
  • When cost efficiency is important in routine experiments.
• Choose AlbuMAX™ II:
  • For specialized or high-performance applications, such as monoclonal antibody production or high-demand recombinant protein expression.
  • For cell lines with significant lipid metabolic requirements.

Storage and Handling

• Storage Conditions:
  • Both products should be stored at 2–8°C in a tightly sealed container.
• Preparation:
  • Both require reconstitution in sterile water or media, followed by sterile filtration.

Summary

• AlbuMAX™ I is suitable for less demanding cell culture systems, providing sufficient lipid supplementation for general applications.
• AlbuMAX™ II offers superior lipid content and is optimized for advanced, high-yield applications in biotechnology and pharmaceutical production.