CrAg® LFA CRYPTOCOCCAL ANTIGEN test kit for 50 tests

Cryptococcal meningitis is one of the most common opportunistic infections among HIV/AIDS patients, estimating more than 220,000 cases and 181,000 deaths worldwide each year.1 Early detection and treatment of infection are key to reducing the mortality associated with this disease.

The CrAg LFA is highly sensitive and specific, with a rapid turnaround time of just 10 minutes.

1) Rajasingham R, Smith RM, Park BJ, et al. Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis. Lancet Infect Dis. 2017;17(8):873-881.

2) IMMY CrAg LFA US IFU                                         4) Binnicker MJ, et al. Comparison of Four Assays for the Detection   3) IMMY CrAg LFA International IFU                        of Cryptococcal Antigen. Clin and Vacc Immuno. 2012; 19(18):1988.

  When tested against Meridian’s EIA, the CrAg LFA showed high diagnostic performance in 197 serum specimens. The Crag LFA agreed with 100% of the Meridian EIA positive test results, and 93% of the Meridian EIA negative test results.

2) IMMY CrAg LFA Domestic IFU

3) IMMY CrAg LFA International IFU

When tested against culture and India ink, the CrAg LFA showed high diagnostic performance in all specimen types.

From the table above, we can conclude that the CrAg LFA will correctly generate a positive result for 100% of patients with Cryptococcus in serum and CSF samples, and 98% in Plasma and Whole Blood samples.2,3

The CrAg LFA will correctly generate a negative result for 100% of patients withoutCryptococcus in serum, CSF, and Plasma samples, and 94% in Whole Blood samples.2,3

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