Applied Biosystems™ AutoMate Express™ Forensic DNA Extraction System

The Applied Biosystems™ AutoMate Express™ Forensic DNA Extraction System is a robust, benchtop instrument specifically designed for automated DNA extraction from forensic samples. The system integrates with PrepFiler Express and PrepFiler Express BTA chemistries, which are pre-packaged in pre-filled, foil-sealed cartridges. The unique system is tailored to improve DNA yield and purity, making it ideal for downstream applications such as STR (Short Tandem Repeat) analysis, quantitative PCR, and genotyping.

By automating the process, the AutoMate Express offers an efficient, time-saving, and cost-effective solution for forensic laboratories that require reliable and high-throughput DNA extraction from a variety of challenging sample types. The system can process between 1 to 13 samples per run, providing high-quality DNA that is free of PCR inhibitors and suitable for a variety of forensic DNA analyses.

Key Features & Benefits

✅ High DNA Yield and Purity

• Designed to extract high-quality DNA from routine and challenging forensic samples, ensuring successful downstream analysis.
• DNA is free of PCR inhibitors, allowing for accurate quantitative real-time PCR and STR analysis.

✅ Customizable Elution Volumes

• Seven elution volumes available, ranging from 20 μL to 250 μL, offering flexibility for different sample types and purification needs.

✅ Fast and Efficient Separation

• The PrepFiler LySep Column technology streamlines the off-line lysis process, separating the substrate from lysate with minimal manual handling.
• Quick centrifugation ensures efficient lysate flow through the burstable membrane while substrates remain behind, reducing contamination risks.

✅ Automated, High-Throughput System

• Processes 1 to 13 samples in a single run, making it ideal for high-throughput environments and routine forensic DNA extraction.
• Pre-programmed protocols simplify operation and ensure consistency in results.

✅ Closed System for Minimal Contamination Risk

• The closed system design reduces the risk of contamination and sample transposition events during processing, ensuring data integrity.

✅ Convenient and Easy-to-Use

• The PrepFiler Express Kits come with all necessary reagents and components for 52 DNA extractions, making it convenient and easy to use without additional reagents.
• The system requires minimal hands-on time and automated handling for efficient results.

✅ Streamlined Workflow

• Pre-filled, foil-sealed cartridges reduce setup time and eliminate handling errors during the preparation process.
• Easy-to-implement with integrated, pre-programmed protocols for nucleic acid purification from forensic samples.

Specifications

Applications

• Forensic DNA Extraction:
  • Ideal for extracting DNA from forensic samples such as blood, tissue, and bodily fluids for STR profiling and genotyping.
• Routine PCR Applications:
  • Suitable for real-time PCR analysis, especially in forensic, clinical research, and pathogen detection labs.
• Sample Preparation for High-Throughput Testing:
  • Perfect for high-throughput environments, such as criminal investigations and forensic DNA analysis.
• DNA Extraction from Challenging Samples:
  • Efficiently extracts DNA from difficult samples, including bones, teeth, and old forensic evidence.

Why Choose the AutoMate Express™ Forensic DNA Extraction System?

✅ High-Quality DNA Yield: Ensures pure DNA free of PCR inhibitors, ideal for STR analysis and quantitative PCR.

✅ Versatility: Supports various sample types, including routine and challenging forensic samples.

✅ Automated and High-Throughput: Automates the extraction of up to 13 samples per run, minimizing manual intervention and errors.

✅ User-Friendly: Pre-filled cartridges and pre-programmed protocols make the system easy to use and implement in a laboratory setting.

✅ Minimized Contamination Risk: Closed system design reduces the chance of contamination or sample transposition.