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Sigma-Aldrich AmberChrom™ 1X4 chloride form, 20-50 mesh, Anion Exchange Resin
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Linear Formula: (C10H12 · C10H10 · C8H8 · C3H9N)X
CAS Number: 69011-19-4
Specifications:
| Application | Ion Exchange Chromatography | ||
| Storage Temperature | Ambient | ||
| Product Type | Ion Exchange Resins | Forms | Solid |
| Product Brand | Sigma-Aldrich | ||
| Product Grade | Analytical grade | Formula | (C₁₀H₁₂ · C₁₀H₁₀ · C₈H₈ · C₃H₉N)X |
Sigma-Aldrich AmberChrom™ 1X4 is a strongly basic Type I anion exchange resin in the chloride form, designed for high-efficiency removal of anionic contaminants from aqueous solutions. This gel-type resin features a quaternary ammonium functional group on a styrene-divinylbenzene matrix, with 4% cross-linkage and >50% moisture content for excellent ion exchange kinetics.
Used widely in pharmaceutical purification, environmental testing, and industrial water treatment, AmberChrom™ 1X4 is equivalent to Dowex® 1X4-50 and compliant with FDA 21 CFR 173.25 for food-grade water purification.
Key Features
- Strongly basic (Type I) anion exchange resin in chloride form
- Quaternary ammonium active groups for high anion exchange capacity
- Mesh size 20–50 for optimal flow and resolution
- Suitable for use in LPLC and column chromatography
- Operates across a wide pH range (0–14)
- High moisture content (>50%) for fast kinetics
- Thermally stable up to 99 °C (Cl⁻ form) and 66 °C (OH⁻ form)
- Meets FDA Food Additive Regulation 21 CFR 173.25
- Regenerable with NaCl or NaOH solutions
Chemical & Physical Properties
| Property | Specification |
|---|---|
| Product Name | AmberChrom™ 1X4 Chloride Form |
| Former Name | Dowex 1X4-50 Chloride Form |
| Ion Exchange Type | Strong Base Anion (Type I) |
| Functional Group | Quaternary Ammonium |
| Polymer Matrix | Styrene-Divinylbenzene (gel type) |
| Cross-Linkage | 4% |
| Form | Beads |
| Particle Size | 20–50 mesh |
| Moisture Content | >50% |
| Total Exchange Capacity | 1.0 meq/mL (wet bed volume) |
| Operating pH Range | 0–14 |
| Max Temp (Cl⁻ Form) | 99 °C |
| Max Temp (OH⁻ Form) | 66 °C |
| Recommended Use | Anion exchange chromatography, deionization, fluoride removal, capillary electrophoresis, NMR sample prep |
Applications
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Pharmaceuticals & Fine Chemical Purification
Used for removal of fluoride, sulfate, iodinated contrast agents, and other anions from formulations and solutions. -
Environmental & Wastewater Treatment
Applied in trace contaminant removal, such as chromates and arsenates, and in fluoride decontamination systems. -
Food & Beverage Industry
Compliant with FDA guidelines for use in food-grade water purification processes. -
Analytical Chemistry & Chromatography
Supports applications in ¹¹B NMR, capillary electrophoresis, and high-resolution ionic separation. -
Industrial Water Deionization
Works with cation exchange resins in dual-bed or mixed-bed water purification systems.
Handling Notes
This resin has not been pre-washed. It is recommended to pre-condition with suitable elution and rinsing (e.g., NaCl or NaOH followed by deionized water) before use.
Ordering Information
| Catalog # | Pack Size | Packaging |
|---|---|---|
| 428612-500G | 500 g | Plastic container |
Sigma-Aldrich AmberChrom™ 1X4 Chloride Form is a versatile, high-capacity anion exchange resin ideal for chromatographic separations, pharmaceutical purification, environmental monitoring, and water deionization. Its FDA compliance, strong performance across pH and temperature ranges, and reusability make it a reliable choice for both laboratory and industrial applications.