Vancomycin hydrochloride, Cell culture tested

Vancomycin hydrochloride is a glycopeptide antibiotic commonly used to inhibit bacterial cell wall synthesis. It achieves its antibacterial effects by targeting and disrupting the formation of peptidoglycan polymers essential for bacterial cell wall structure. This compound is often employed in combination with cefotaxime or carbenicillin for enhanced efficacy.

Key Features:

1. Antibacterial Mechanism:
   • Inhibits peptidoglycan polymerization, weakening the bacterial cell wall and leading to bacterial lysis.
2. Potency and Efficacy:
   • Potency: 1099 mcg/mg.
   • Effective against gram-positive bacteria, including Staphylococcus aureus and Clostridium difficile.
3. Cell Culture Grade:
   • Tested for cell culture applications, ensuring reliability in research settings.
4. Chemical Properties:
   • Formula: C₆₆H₇₅Cl₂N₉O₂₄·HCl
   • Molecular Weight: 1485.71 g/mol
5. Applications:
   • Antibiotic in microbial cell culture.
   • Research on antibacterial mechanisms and resistance studies.
   • Pharmaceutical formulation as a therapeutic antibiotic.

Specifications:

Applications:

1. Antibacterial Research:
   • Study bacterial cell wall synthesis inhibition.
   • Investigate resistance mechanisms in gram-positive bacteria.
2. Cell Culture:
   • Used as a supplement in microbial cultures to control bacterial contamination.
3. Combination Therapy Studies:
   • Explore synergistic effects when combined with cefotaxime or carbenicillin.
4. Pharmaceutical Research:
   • Supports the development of formulations targeting gram-positive infections.

Storage and Handling:

• Storage Conditions:
  • Store refrigerated at 2–8°C to maintain stability and potency.
• Handling Precautions:
  • May cause irritation; handle with care using appropriate PPE.
  • Avoid exposure to moisture and direct sunlight.

Advantages:

• High Potency: Ensures effective inhibition of bacterial growth.
• Cell Culture Tested: Reliable for use in biological and microbiological applications.
• Broad Applicability: Effective against a wide range of gram-positive bacteria.

Legal and Safety Information:

• Irritant Warning: Handle in compliance with laboratory safety protocols.
• Storage Precaution: Keep in a cool, dry place away from incompatible materials.

The Apollo Scientific Vancomycin Hydrochloride is a versatile and potent antibiotic essential for microbiological research and pharmaceutical development. Its tested performance in cell culture applications and compatibility with other antibiotics makes it a valuable tool for scientific and clinical studies.