Thermo Scientific™ Pierce™ Detergent Removal Resin, 10mL

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Specifications:
Application Protein Purification
Storage Temperature 2-8°C
Product Type Molecular Biology Reagent Forms Liquid
Product Brand Thermo Fisher Scientific™
Product Grade Molecular Biology

Thermo Scientific™ Pierce™ Detergent Removal Resins provide a rapid and highly efficient method for eliminating detergents and surfactants from protein and peptide samples. Detergent contamination can severely impact ELISA, isoelectric focusing (IEF), and mass spectrometry (LC-MS/MS, MALDI-MS) by interfering with binding, elution, and ionization processes. These proprietary resins remove over 95% of detergent content in under 15 minutes with minimal sample loss, ensuring high-quality analytical results.

Designed for versatility, Pierce Detergent Removal Resins are available in multiple pre-packed formats—including spin columns, bulk resin, and 96-well plates—making them ideal for both low- and high-throughput applications.

Key Features & Benefits

  • High-Efficiency Removal – Eliminates >95% of common detergents such as SDS, Triton™ X-100, NP-40, and CHAPS.
  • Fast Processing – Complete detergent cleanup in less than 15 minutes.
  • Minimal Sample Loss – Preserves protein and peptide integrity during purification.
  • Multiple Formats – Spin columns, bulk resin, and 96-well plates for flexible workflows.
  • Improved Downstream Results – Enhances performance in ELISA, IEF, LC-MS/MS, and MALDI-MS.

Available Formats & Catalog Numbers

Catalog NumberFormat / CapacityProduct TypeQuantity
87776125 μL Spin ColumnsSpin Column25 columns
87777500 μL Spin ColumnsSpin Column25 columns
877782 mL Spin ColumnsSpin Column5 columns
877794 mL Spin ColumnsSpin Column5 columns
8778010 mL Bulk ResinDetergent Removal Resin1 bottle
8830496-Well Spin PlatesSpin Plate2 plates

Applications

  • Sample preparation for mass spectrometry (LC-MS/MS, MALDI-MS)
  • Detergent removal prior to ELISA or isoelectric focusing
  • Cleanup of tryptic digests in proteomics workflows
  • Removal of high concentrations of surfactants from protein and peptide samples

Product Specifications

ParameterDetail
Product LinePierce™
Product TypeDetergent Removal Resin / Spin Column / Spin Plate
Purification TargetDetergent removal from proteins and peptides
Column TypeProprietary resin, affinity-based
Stationary PhaseProprietary ligand
Unit SizeEach
Storage ConditionsStore at 4°C
Preservatives0.15 M NaCl, 0.05% sodium azide
Intended UseFor research use only. Not for use in diagnostic procedures.


Thermo Scientific™ Pierce™ Detergent Removal Resins deliver fast, efficient, and reproducible detergent cleanup for sensitive protein and peptide analyses. With multiple formats available, they provide a flexible and reliable solution for laboratories performing mass spectrometry, immunoassays, and electrophoretic applications.

  • Pack Size:   10 mL 25 x 125 μL Columns 25 x 500 μL Columns 5 x 2 mL Columns 5 x 4 mL Columns 2 x 96-well Plates

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