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Thermo Scientific™ NanoDrop™ OneC Microvolume UV-Vis Spectrophotometer
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Specifications:
| Application | molecular biology | Warranty | 1 Year |
| Storage Temperature | Room Temperature | ||
| Product Type | Laboratory Equipment | ||
| Product Brand | Thermo Fisher Scientific™ | ||
| Product Grade | Molecular Biology | ||
The NanoDrop™ One Microvolume UV-Vis Spectrophotometer is an advanced, ergonomic tool designed for rapid and accurate quantification of biomolecules like DNA, RNA, and proteins. With its microvolume pedestal technology requiring just 1–2 μL, it eliminates the need for cuvettes and enables full-spectrum analysis in seconds, providing researchers with reliable data for downstream applications.
Key Features
- Acclaro™ Sample Intelligence Technology:
- Detects contaminants and provides corrected concentration values.
- Prevents downstream application failures by offering alerts and guidance.
- Measurement Efficiency:
- Requires only 1–2 μL of sample.
- Measures DNA, RNA, and proteins with a dynamic range of 2–27,500 ng/μL.
- User-Friendly Operation:
- 7-inch high-definition touchscreen with intuitive software.
- Built-in methods for nucleic acid, protein, and colorimetric assays.
- Advanced Connectivity:
- USB, Ethernet, and Wi-Fi* for data transfer.
- Thermo Fisher Cloud integration for collaboration and remote data access.
- Cuvette Compatibility (NanoDrop™ OneC):
- Adds a cuvette position for kinetic studies and dilute sample measurements.
- Includes temperature control and stirring capabilities.
Comparison Table: NanoDrop™ One vs. NanoDrop™ OneC
| Feature | NanoDrop™ One | NanoDrop™ OneC |
|---|---|---|
| Sampling Modes | Pedestal only | Pedestal and cuvette |
| Cuvette Holder | Not available | Included (supports temperature control & stirring) |
| Kinetics Experiments | Not supported | Supported |
| Detection Range (dsDNA) | 2 – 27,500 ng/μL | 0.2 – 27,500 ng/μL |
| Measurement Time | 8 seconds | 8 seconds |
| Dynamic Range (Protein) | 0.06 – 820 mg/mL (BSA) | 0.003 – 820 mg/mL (BSA) |
| Temperature Control | Not available | Available for cuvette |
| Connectivity | USB, Ethernet, Wi-Fi* | USB, Ethernet, Wi-Fi* |
| Dimensions (L × W × H) | 20 × 25.4 × 32.3 cm | 20 × 25.4 × 32.3 cm |
| Weight | 3.6 kg | 3.6 kg |
| Sample Volume | 1–2 μL | 1–2 μL (pedestal); varies for cuvette |
| Applications | Nucleic acids, protein quantification, UV-Vis spectroscopy | Expanded to include kinetics and bacterial OD600 |
Specifications
| Parameter | Details |
|---|---|
| Spectral Range | 190–850 nm |
| Pathlength | 0.030–1.0 mm (auto-ranging) |
| Photometric Range | Pedestal: 0–550 A; Cuvette: 0–1.5 A |
| Photometric Accuracy | ±3% at 0.97 A |
| Sample Volume | Minimum 1 μL |
| Repeatability | 0.002 A (1.0 mm path) or 1% CV |
| Display | 7-inch HD touchscreen (1280 × 800 pixels) |
| Detector Type | CMOS linear image sensor |
| Power Consumption | Operating: 12–18 W; Standby: 5 W |
| Weight | 3.6 kg (7.9 lbs) |
| Light Source | Xenon flash |
| Operating System | Android™ |
| Certifications | CE, UL/CSA |
Applications
- Nucleic Acids (DNA/RNA): Quantify and qualify purity ratios (A260/A280, A260/A230).
- Protein Analysis: Measure purified proteins (A280), colorimetric protein assays (BCA, Bradford, Lowry).
- Kinetics Studies (OneC): Use cuvette for time-based experiments with temperature control.
- UV-Vis Assays: Measure peptides, gold nanoparticles, dyes, and more across a wide spectral range.
With its versatile features, the NanoDrop™ One and OneC Spectrophotometers empower researchers to obtain precise results efficiently, driving advancements in biopharmaceutical, bioscience, and academic research.
- Model: NanoDrop OneC NanoDrop One