Thermo Scientific™ Glutaraldehyde 50% in aqueous solution

Glutaraldehyde is used as a cross linking agent for gelatin, poly(vinyl alcohol) and polyheptapeptides. It is also used as a fixative for electron microscopy and as disinfectants. It provides water resistance to protein and polyhydroxy compounds by reacting through cross linking. It acts as an intermediate for the production of resins, dyestuffs, pharmaceuticals, photographic films and for stabilization of proteins on agarose beads, activation of polystyrene and glass for immobilization of antibodies and antigens and coupling peptides onto carrier proteins.

Applications

Glutaraldehyde is used as a cross linking agent for gelatin, poly(vinyl alcohol) and polyheptapeptides. It is also used as a fixative for electron microscopy and as disinfectants. It provides water resistance to protein and polyhydroxy compounds by reacting through cross linking. It acts as an intermediate for the production of resins, dyestuffs, pharmaceuticals, photographic films and for stabilization of proteins on agarose beads, activation of polystyrene and glass for immobilization of antibodies and antigens and coupling peptides onto carrier proteins.

Solubility

Miscible with water, acetone, dichloromethane, ethylacetate, isopropanol, n-hexane and toluene.

Notes

Incompatible with strong oxidisng agents, strong acids and strong bases.

RUO – Research Use Only

General References:

1. Woods, A.; Patela, A.; Spina, D.; Riffo-Vasquez, Y.; Babin-Morgan, A.; Rosales, R. T. M.; Sunassee, K.; Clark, S.; Collins, H.; Bruce, K.; Dailey, L. A.; Forbes, B. In vivo biocompatibility, clearance, and biodistribution of albumin vehicles for pulmonary drug delivery. J. Controlled Release 2015, 210, 1-9.
2. Lu, W.; Ma, M.; Xu, H.; Zhang, B.; Cao, X.; Guo, Y. Gelatin nanofibers prepared by spiral-electrospinning and cross-linked by vapor and liquid-phase glutaraldehyde. Mater. Lett. 2015, 140, 1-4.