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Thermo Scientific™ Dextran sulphate sodium salt, M.W. ~ 40,000
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CAS Number :
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Specifications:
| Storage Temperature | 2-8°C | ||
| Product Type | Biochemical Reagent | Forms | Powder |
| Product Brand | Thermo Fisher Scientific™, Alfa Aesar | ||
| Product Grade | Analytical grade | ||
Thermo Scientific™ Dextran Sulfate Sodium (DSS) Salt is a high-purity, polyanionic derivative of dextran used extensively in biomedical and clinical research. DSS is produced by esterification of dextran with chlorosulfonic acid, yielding a sodium salt form that is freely soluble in water and salt solutions, forming a stable, clear solution.
This M.W. ~40,000 dextran sulfate sodium salt is widely recognized as a reliable reagent for inducing experimental colitis in laboratory animals, making it an essential tool for Inflammatory Bowel Disease (IBD) research. Additionally, DSS has applications in antiviral research and as a biochemical reagent for nucleic acid hybridization and protein stabilization.
Key Features & Benefits
✅ M.W. ~40,000 – Optimal molecular weight for colitis induction models
✅ Sulfur Content ~17% – Corresponds to 1.9 sulfate groups per glucosyl residue
✅ Highly Soluble & Stable – Freely dissolves in water and salt solutions
✅ Reliable IBD Model Agent – Induces spontaneous colitis in animal studies
✅ Versatile Biomedical Applications – Used in antiviral studies, nucleic acid research, and more
✅ Proven Research Reagent – Widely cited in colitis, cancer, and gastrointestinal research
Applications
🔬 Inflammatory Bowel Disease (IBD) Research – DSS-induced colitis model mimics human ulcerative colitis
🦠 Colitis-Associated Cancer (CAC) Studies – Evaluates therapeutic interventions for IBD-related cancers
🧬 Antiviral Research – Investigates DSS as a potential antiviral agent
🛠️ Nucleic Acid Hybridization – Used in biochemical applications for DNA and RNA studies
⚗️ Protein Stabilization & Biochemical Research – Serves as a polyanionic stabilizing agent
Product Specifications
| Attribute | Details |
|---|---|
| Chemical Name | Dextran Sulfate Sodium Salt |
| Molecular Formula | (C₆H₇Na₃O₁₄S₃)ₙ |
| Molecular Weight | ~40,000 |
| Sulfur Content | ~17% |
| Sulfur Substitution | ~1.9 sulfate groups per glucosyl residue |
| Form | White to off-white powder |
| Solubility | Freely soluble in water and salt solutions |
| pH (1% Solution) | Stable and clear |
| Application | Colitis Research, IBD Models, Antiviral Research, Nucleic Acid Hybridization |
| Storage Conditions | Refrigerator (2–8°C) |
| CAS Number | 9011-18-1 |
| MDL Number | MFCD00081551 |
Usage Guidelines
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For Colitis Induction in Animal Models:
- Oral administration via drinking water in mice induces spontaneous colitis
- Commonly used in preclinical studies of IBD treatments
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For Biochemical Applications:
- Dissolves easily in aqueous solutions for nucleic acid hybridization
- Used as a polyanionic reagent in various molecular biology assays
Regulatory & Safety Information
⚠️ For Research Use Only. Not intended for diagnostic, therapeutic, or human/animal consumption.
- Use in a well-ventilated laboratory with appropriate safety precautions
- Refer to the Safety Data Sheet (SDS) for handling and disposal guidelines
Why Choose Thermo Scientific™ Dextran Sulfate Sodium Salt?
🔹 Optimized for IBD & Colitis Research – Proven reagent for colitis modeling
🔹 High Purity & Reproducibility – Ensures consistent experimental results
🔹 Broad Biomedical Applications – Used in virology, molecular biology, and inflammation research
🔹 Reliable Supply & Packaging – Available in multiple sizes to suit research needs
For bulk orders, technical support, or additional information, contact LabMart Limited today.
- Pack Size: 100g 25g