Thermo Scientific™ 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic cid 97% (Trolox)
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Formula: C₁₄H₁₈O₄
CAS Number: 53188-07-1
Specifications:
Application | Colorimetric Assay, ELISA-Based Assays | ||
Storage Temperature | Ambient | ||
Product Type | Laboratory Chemical | Forms | Powder |
Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
Product Grade | Analytical grade | Formula | C₁₄H₁₈O₄ |
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, commonly referred to as Trolox, is a water-soluble analogue of vitamin E (α-tocopherol). It is widely used as a standard antioxidant in biochemical and pharmaceutical research for the quantitative analysis of antioxidant capacity, including ABTS and ORAC assays.
With a high purity level of ≥97% and well-characterized physicochemical properties, Trolox is the preferred reference compound in studies involving reactive oxygen species (ROS), free radical scavenging, and lipid peroxidation inhibition.
Key Features
- ≥97% purity by titration with NaOH
- Powerful antioxidant standard in biochemical assays
- Water-soluble analog of α-tocopherol (vitamin E)
- Consistent melting range (187–194 °C)
- Crystalline powder, easy to handle and dissolve
- GHS07 classification – handle with standard laboratory PPE
- Stable at ambient conditions
Applications
- Reference standard for antioxidant capacity assays (e.g., ORAC, ABTS, DPPH)
- Research on oxidative stress and cellular protection mechanisms
- Assessment of free radical scavenging activity
- Nutraceutical and cosmetic ingredient evaluation
- Used in biomedical, food science, and pharmaceutical R&D
- Alternative to α-tocopherol in aqueous systems
Chemical & Physical Properties
Property | Specification |
---|---|
Chemical Name | 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid |
Common Name | Trolox |
CAS Number | 53188-07-1 |
Molecular Formula | C₁₄H₁₈O₄ |
Molecular Weight | 250.29 g/mol |
MDL Number | MFCD00006846 |
Melting Point | 187–194 °C |
Appearance | White to light beige crystalline powder |
Titration Purity | ≥96.0% (NaOH) |
Storage Conditions | Ambient |
Hazard Classification | GHS07 – Irritant |
Available Packaging
Catalog Number | Pack Type | Pack Size | |
---|---|---|---|
218940010 | Glass bottle | 1 g | |
218940050 | Glass bottle | 5 g | |
218940250 | Glass bottle | 25 g |
Thermo Scientific™ Trolox, 97% is a gold-standard antioxidant reference reagent widely used in redox biology, food chemistry, and nutraceutical science. Its excellent solubility and stability, combined with high purity, make it essential for standardized antioxidant evaluations and comparative studies.
- Pack Size: 1g 5g 25g