Thermo Scientific™ 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic cid 97% (Trolox)

6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, commonly referred to as Trolox, is a water-soluble analogue of vitamin E (α-tocopherol). It is widely used as a standard antioxidant in biochemical and pharmaceutical research for the quantitative analysis of antioxidant capacity, including ABTS and ORAC assays.

With a high purity level of ≥97% and well-characterized physicochemical properties, Trolox is the preferred reference compound in studies involving reactive oxygen species (ROS), free radical scavenging, and lipid peroxidation inhibition.

Key Features

• ≥97% purity by titration with NaOH
• Powerful antioxidant standard in biochemical assays
• Water-soluble analog of α-tocopherol (vitamin E)
• Consistent melting range (187–194 °C)
• Crystalline powder, easy to handle and dissolve
• GHS07 classification – handle with standard laboratory PPE
• Stable at ambient conditions

Applications

• Reference standard for antioxidant capacity assays (e.g., ORAC, ABTS, DPPH)
• Research on oxidative stress and cellular protection mechanisms
• Assessment of free radical scavenging activity
• Nutraceutical and cosmetic ingredient evaluation
• Used in biomedical, food science, and pharmaceutical R&D
• Alternative to α-tocopherol in aqueous systems

Chemical & Physical Properties

Available Packaging

Thermo Scientific™ Trolox, 97% is a gold-standard antioxidant reference reagent widely used in redox biology, food chemistry, and nutraceutical science. Its excellent solubility and stability, combined with high purity, make it essential for standardized antioxidant evaluations and comparative studies.