Sigma-Aldrich α-D-Glucose 1-phosphate disodium salt hydrate ≥97% (Enzymatic Purity, anhydrous)

High-Purity Glucose-1-Phosphate for Biochemical & Metabolic Research

Sigma-Aldrich α-D-Glucose 1-Phosphate Disodium Salt Hydrate (≥97%) is a high-purity carbohydrate reagent widely used in biochemical research, metabolic studies, and glycogen metabolism analysis. This synthetically derived α-D-glucose phosphate plays a key role in glycogenolysis, glycolysis, and glycogenesis, making it an essential compound for enzymatic reactions, metabolic pathway studies, and agricultural applications.

With a water solubility of 50 mg/mL, this white powder is ideal for enzymatic assays, sugar metabolism investigations, and biochemical applications requiring high purity and enzymatic specificity.

Key Features & Benefits

✅ High Enzymatic Purity (≥97%) – Ensures accurate and reproducible biochemical results

✅ Essential Metabolic Intermediate – Used in glycolysis, glycogenesis, and glycogenolysis

✅ Synthetic α-D-Glucose Phosphate – Provides high consistency and batch reliability

✅ Low Impurity Levels – Contains ≤0.1 mol% glucose & ≤0.5 mol% α-D-glucose 1,6-diphosphate

✅ Highly Soluble in Water (50 mg/mL) – Allows for easy preparation of solutions

✅ Stable Storage (-20°C) – Maintains long-term stability for research applications

Technical Specifications

Biochemical & Physiological Actions

• Key Intermediate in Glycogen Metabolism:
  • Glycogenolysis: Glucose-1-phosphate (G1P) is produced from glycogen via glycogen phosphorylase.
  • Glycolysis: G1P is converted to glucose-6-phosphate (G6P) by phosphoglucomutase, allowing entry into glycolysis.
  • Glycogenesis: During glycogen synthesis, phosphoglucose isomerase converts glucose-6-phosphate back to glucose-1-phosphate.
• Used in Enzyme Activity Studies:
  • Investigates glycogen phosphorylase, phosphoglucomutase, and phosphoglucose isomerase functions in metabolic pathways.
  • Plays a role in nucleotide sugar biosynthesis for UDP-glucose formation.

Applications

🧪 Biochemical Research & Glycogen Metabolism Studies – Key substrate for enzymatic activity assays

🔬 Metabolic Pathway Investigations – Used in glycolysis, glycogenesis, and carbohydrate metabolism research

🏭 Agricultural & Food Science Research – Studies starch biosynthesis and plant carbohydrate storage

💊 Pharmaceutical & Biomedical Research – Explores sugar metabolism in disease models

Common Use Cases

1️⃣ Glycogenolysis Studies – Evaluates glycogen phosphorylase enzyme activity.

2️⃣ Metabolic Pathway Research – Examines glucose metabolism in energy production.

3️⃣ Carbohydrate Biochemistry Research – Investigates sugar transport and enzymatic conversions.

4️⃣ Agricultural & Starch Biosynthesis Studies – Explores glucose utilization in plant metabolism.

Storage & Handling Guidelines

1️⃣ Store at -20°C – Prevents degradation and maintains enzymatic purity.

2️⃣ Prepare Fresh Solutions When Needed – Avoid long-term storage of aqueous solutions.

3️⃣ Use Standard Laboratory Safety Precautions – Minimize moisture exposure and contamination risk.

Ordering Information

Regulatory & Safety Information

⚠️ For Research Use Only (RUO). Not intended for clinical or therapeutic applications.

⚠️ Use Protective Equipment (PPE). Prevent exposure to airborne particles.

⚠️ Store Properly to Maintain Stability & Purity.

Why Choose Sigma-Aldrich α-D-Glucose 1-Phosphate Disodium Salt Hydrate?

🔹 High Enzymatic Purity (≥97%) for Reliable Research Results

🔹 Essential Substrate for Glycogen Metabolism Studies

🔹 Low Impurities for Accurate Biochemical & Enzymatic Assays

🔹 Highly Soluble in Water for Easy Preparation of Solutions

🔹 Available in Multiple Pack Sizes for Laboratory & Industrial Use

For bulk orders, technical support, or additional information, contact LabMart Limited today. 🚀