MCE 1,2-Distearoyl-sn-glycerol (DSG), ≥98.0%

1,2-Distearoyl-sn-glycerol (DSG) is a diacylglycerol (DAG) lipid consisting of two stearic acid (C18:0) chains esterified at the sn-1 and sn-2 positions of the glycerol backbone. Classified as a neutral lipid and endogenous metabolite, DSG plays an important role in lipid metabolism and signaling pathways.

In research applications, 1,2-Distearoyl-sn-glycerol is widely used as an internal standard for the quantitative analysis of diacylglycerol (DAG) molecular species and related phospholipids, particularly in neuroscience and brain lipidomics studies, including rat brain lipid profiling.

Intended Use

• For research use only (RUO)
• Not for human or veterinary use
• Intended for:
  • Lipidomics and metabolomics research
  • Quantitative DAG analysis
  • Phospholipid profiling
  • Neuroscience and brain lipid studies
  • Analytical method development and validation

Chemical & Physical Properties

Chemical Structure Information

• SMILES:
  OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O

This structure represents a saturated diacylglycerol, commonly used as a stable reference lipid in analytical workflows.

Functional & Biochemical Notes

• Member of the diacylglycerol (DAG) lipid class
• Used as an internal standard for:
  • DAG molecular species quantification
  • Phospholipid and neutral lipid analysis
• Supports accurate measurement in:
  • LC-MS / MS-based lipidomics
  • HPLC and GC lipid analysis
• Particularly relevant in rat brain lipid profiling, where DAG signaling plays a role in neuronal function

Applications

• Lipidomics and metabolomics
• Diacylglycerol (DAG) quantification
• Brain and neuroscience lipid research
• Phospholipid metabolism studies
• Internal standard for analytical chemistry
• Lipid signaling pathway research

Clinical Research Context

Although supplied strictly for research use, DSG has appeared in clinical research references, reflecting broader interest in lipid metabolism:

(Note: product itself is not approved for clinical use.)

Packaging & Available Sizes

Storage & Stability

Key Advantages

• High-purity diacylglycerol standard (≥98.0%)
• Structurally well-defined and reproducible
• Ideal internal standard for DAG analysis
• Suitable for advanced lipidomics workflows
• Available in multiple pack sizes for laboratory flexibility

1,2-Distearoyl-sn-glycerol (DSG) is a high-quality diacylglycerol research compound widely used as an internal standard in lipidomics and phospholipid analysis, particularly in neuroscience and brain lipid studies. Its stability, purity, and well-defined structure make it an essential reagent for quantitative lipid analysis and metabolic research.