Liofilchem™ MTS™ Meropenem MRP 0.002-32, MIC Test strips

The Liofilchem™ MTS™ Meropenem MIC Test Strips are advanced tools for determining the Minimum Inhibitory Concentration (MIC) of Meropenem against bacterial pathogens. These strips utilize gradient diffusion technology to provide precise, reliable, and reproducible results for antimicrobial susceptibility testing (AST). Designed to meet the needs of clinical, pharmaceutical, and research laboratories, they are particularly valuable for studying carbapenem-resistant organisms.

Key Features

1. Broad MIC Range:
   • Covers concentrations from 0.002 µg/mL to 32 µg/mL, enabling susceptibility testing of a wide variety of bacterial strains.
2. Gradient Diffusion Technology:
   • Provides a continuous concentration gradient, ensuring precise MIC determination for both susceptible and resistant strains.
3. High Sensitivity and Specificity:
   • Effective for detecting low-level resistance in Gram-negative pathogens, including Enterobacterales and Pseudomonas aeruginosa.
4. Versatile Application:
   • Suitable for testing carbapenem-resistant organisms, hospital-acquired infections, and multidrug-resistant bacteria.
5. Compliant with CLSI and EUCAST Standards:
   • Delivers reliable results that meet global regulatory guidelines for antimicrobial susceptibility testing.

Applications

• Clinical Diagnostics:
  • Determine the susceptibility of pathogens to Meropenem, particularly in critical care settings.
  • Guide treatment strategies for Gram-negative infections caused by multidrug-resistant organisms.
• Research and Development:
  • Investigate resistance mechanisms in carbapenemase-producing organisms.
  • Study the efficacy of Meropenem in combination therapies.
• Pharmaceutical Testing:
  • Evaluate the pharmacodynamics of Meropenem in preclinical studies.

Testing Procedure

1. Preparation:
   • Prepare a bacterial suspension to 0.5 McFarland standard.
   • Spread the suspension uniformly on Mueller-Hinton agar plates.
2. Application:
   • Place the MTS™ Meropenem strip onto the agar surface using sterile forceps.
3. Incubation:
   • Incubate at 35–37°C for 16–20 hours in aerobic conditions.
4. Interpretation:
   • Read the MIC value where the bacterial inhibition zone intersects the strip.

Storage and Stability

• Ensure strips are stored in a moisture-free, sterile environment.
• Avoid repeated freeze-thaw cycles.

Technical Specifications

Advantages

1. Reliable Detection:
   • Accurately identifies resistance in carbapenem-resistant and beta-lactamase-producing pathogens.
2. Wide MIC Range:
   • Facilitates testing of highly susceptible and resistant bacterial strains.
3. Ease of Use:
   • Simple setup and interpretation integrate seamlessly into routine laboratory workflows.
4. Reproducible Results:
   • Ensures consistency and reliability across multiple tests.

Quality Control

Why Choose Liofilchem™ MTS™ Meropenem MIC Test Strips?

The Liofilchem™ MTS™ Meropenem Test Strips provide an accurate, efficient, and standardized approach to MIC determination. With their broad MIC range, compliance with international standards, and reliability in detecting carbapenem resistance, these strips are indispensable for clinical diagnostics, pharmaceutical research, and antimicrobial resistance studies.