Liofilchem™ MTS™ Cefotaxime CTX 0.016-256, MIC Test strips

The Liofilchem™ MTS™ Cefotaxime CTX MIC Test Strips are precise, gradient diffusion-based tools designed for determining the Minimum Inhibitory Concentration (MIC) of Cefotaxime against bacterial isolates. These strips provide accurate quantitative results for antibiotic susceptibility testing (AST), making them essential for clinical microbiology labs, hospitals, and research facilities.

Key Features

1. Gradient Diffusion Technology:
   • The strip contains a predefined gradient of Cefotaxime ranging from 0.016-256  μg/mL.
   • Generates clear, interpretable MIC values directly on an agar plate.
2. High Sensitivity and Specificity:
   • Enables reliable detection of Cefotaxime resistance in Gram-negative pathogens, including ESBL-producing Enterobacteriaceae.
3. Ease of Use:
   • Simple to apply on agar plates, with a visible gradient that simplifies reading MIC endpoints.
4. Broad Compatibility:
   • Suitable for testing both aerobic and facultative anaerobic bacteria.
5. Standardized Results:
   • Fully compatible with EUCAST, CLSI, and other global AST interpretative standards.

Applications

1. Antibiotic Susceptibility Testing:
   • Evaluate the efficacy of Cefotaxime against clinical bacterial isolates.
2. Detection of ESBL-Producing Bacteria:
   • Identify Extended-Spectrum Beta-Lactamase (ESBL) resistance in pathogens like E. coli and Klebsiella pneumoniae.
3. Resistance Monitoring:
   • Track the development of carbapenem-resistant Enterobacteriaceae (CRE) and other multidrug-resistant organisms.
4. Clinical Diagnostics:
   • Provide actionable results for tailoring patient-specific antimicrobial therapies.
5. Pharmaceutical Research:
   • Investigate the MIC of Cefotaxime in experimental studies involving Gram-negative bacteria.

How It Works

1. Preparation:
   • Prepare an agar plate inoculated with a standardized bacterial suspension.
2. Application:
   • Place the Cefotaxime MTS strip on the inoculated plate.
3. Incubation:
   • Incubate at the recommended temperature (typically 35–37°C) for 18–24 hours.
4. Result Interpretation:
   • Read the MIC value where the ellipse of bacterial growth intersects the strip’s gradient scale.

Specifications

Advantages

1. Accuracy:
   • Provides precise MIC values for better therapeutic decision-making.
2. Speed:
   • Results available within 18–24 hours of incubation.
3. Reliability:
   • Ensures consistency across tests due to high manufacturing standards.
4. Versatility:
   • Effective for both routine AST and specialized resistance detection.

Limitations

• Cannot confirm resistance mechanisms; additional molecular testing may be required.
• Requires proper handling and storage to maintain efficacy.

Why Choose Liofilchem™ MTS™ Cefotaxime?

• Efficiency: Combines simplicity with high accuracy in MIC determination.
• Flexibility: Useful for a wide range of bacterial pathogens and clinical scenarios.
• Global Standards Compliance: Supports laboratory workflows aligned with EUCAST and CLSI guidelines.

The Liofilchem™ MTS™ Cefotaxime CTX MIC Test Strips are invaluable for clinical and research applications, enabling reliable susceptibility testing and resistance monitoring for Cefotaxime.