Liofilchem® Griseofulvin AGF Antimicrobial Susceptibility Discs, 10 µg

The Liofilchem® Griseofulvin AGF Antimicrobial Susceptibility Discs (10 µg) are high-quality, standardized discs used in the agar diffusion method (Kirby-Bauer) for antifungal susceptibility testing. Each disc is impregnated with 10 µg of Griseofulvin (AGF), a fungistatic antibiotic widely used in the treatment of dermatophytic infections.

Manufactured in compliance with EUCAST/CLSI standards, these discs ensure reproducibility and accuracy in susceptibility testing, supporting clinical decision-making, epidemiological surveillance, and antifungal stewardship programs.

Key Features

• Contains 10 µg Griseofulvin (AGF) per disc.
• Available in cartridge format (5 × 50 discs) or canister format (250 discs).
• Designed for Kirby-Bauer disc diffusion testing.
• Conforms to EUCAST and CLSI performance standards.
• Ensures consistency, reproducibility, and traceability.
• Long shelf life with reliable disc potency.

Ordering Information

Use Cases

1. Clinical Microbiology Laboratories
   • Routine antifungal susceptibility testing of dermatophytes.
   • Supports patient management by determining Griseofulvin activity against clinical isolates.
2. Hospital Infection Control Programs
   • Monitoring antifungal resistance patterns to optimize treatment guidelines.
3. Public Health and Epidemiological Surveillance
   • Tracking resistance trends in fungal pathogens.
4. Research and Pharmaceutical Development
   • Used in comparative studies of antifungal efficacy.
   • Useful for validating new antifungal compounds against Griseofulvin reference activity.

Clinical Significance

• Griseofulvin is a fungistatic antibiotic primarily active against dermatophytes (Trichophyton, Microsporum, Epidermophyton species).
• It works by disrupting fungal microtubules and inhibiting mitosis.
• Though systemic use has declined in favor of newer antifungals, Griseofulvin remains a reference drug for testing dermatophytic infections and is important for resistance monitoring.
• Using standardized susceptibility discs ensures consistent data for clinical and surveillance purposes, helping clinicians select the most effective antifungal treatment.

The Liofilchem® Griseofulvin AGF Antimicrobial Susceptibility Discs (10 µg) provide a reliable, standardized, and pharmacopoeia-compliant method for antifungal susceptibility testing. With their accuracy, reproducibility, and adherence to EUCAST/CLSI guidelines, these discs are a crucial tool for clinical diagnostics, antifungal stewardship, and mycology research.