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Specifications:
| Application | Cold chain Storage |
| Material | Polycarbonate |
| Storage Temperature | Room Temperature |
| Product Type | Cryogenic Storage |
| Product Brand | Corning |
| Product Grade | Laboratory grade |
Corning® CoolCell® containers are designed for controlled-rate freezing at approximately -1°C per minute when used with a -80°C freezer. This consistent freezing rate is optimal for cryopreserving most cells and cell lines. The alcohol-free design provides a safer, more convenient, and cost-effective solution compared to traditional alcohol-based freezing containers.
Key Features
- Alcohol-Free Design: Eliminates the need for isopropyl alcohol, reducing cost, mess, and risk of contamination.
- Controlled Freezing Rate: Ensures uniform cooling at approximately -1°C per minute, ideal for preserving cell viability.
- Durable and Reusable: Made with cross-linked polyethylene foam and a solid-state core for long-lasting use.
- Non-Absorbent Material: Minimizes impact on freezer temperature and protects nearby frozen samples.
- Ease of Use: Simply invert the container to remove vials, eliminating the need for handling small accessories.
- Color-Coded Options: Available in multiple colors for easy identification.
Advantages
- Cost-Effective: Lower overall cost compared to alcohol-based devices.
- Reproducibility: Ensures consistent and standardized freezing across experiments.
- High Recovery Rates: Promotes better cell recovery and viability post-thaw.
- Environmentally Friendly: Alcohol-free, reducing hazardous waste.
Specifications
| Product Number | Product Name | Capacity | Color Options | Qty./Pack | Qty./Case |
|---|---|---|---|---|---|
| 432000 | CoolCell® for 12 x 1–2 mL Cryogenic Vials | 12 Vials (1–2 mL) | Purple | 1 | 1 |
| 432001 | CoolCell® LX for 12 x 1–2 mL Cryogenic Vials | 12 Vials (1–2 mL) | Purple | 1 | 1 |
| 432002 | CoolCell® LX for 12 x 1–2 mL Cryogenic Vials | 12 Vials (1–2 mL) | Green | 1 | 1 |
| 432003 | CoolCell® LX for 12 x 1–2 mL Cryogenic Vials | 12 Vials (1–2 mL) | Orange | 1 | 1 |
| 432004 | CoolCell® LX for 12 x 1–2 mL Cryogenic Vials | 12 Vials (1–2 mL) | Pink | 1 | 1 |
| 432005 | CoolCell® LX for 12 x 3.5–5.0 mL Cryogenic Vials | 12 Vials (3.5–5.0 mL) | Purple | 1 | 1 |
| 432006 | CoolCell® FTS30 for 30 x 1–2 mL Cryogenic Vials | 30 Vials (1–2 mL) | Purple | 1 | 1 |
| 432007 | CoolCell® FTS30 for 30 x 1–2 mL Cryogenic Vials | 30 Vials (1–2 mL) | Orange | 1 | 1 |
| 432008 | CoolCell® FTS30 for 30 x 1–2 mL Cryogenic Vials | 30 Vials (1–2 mL) | Green | 1 | 1 |
| 432009 | CoolCell® FTS30 for 30 x 1–2 mL Cryogenic Vials | 30 Vials (1–2 mL) | Pink | 1 | 1 |
| 432010 | CoolCell® SV2 for 12 x 2 mL Serum Vials | 12 Serum Vials (2 mL) | Not specified | 1 | 1 |
| 432011 | CoolCell® SV10 for 6 x 10 mL Serum Vials | 6 Serum Vials (10 mL) | Not specified | 1 | 1 |
| 432138 | CoolCell® LX 4-Pack (12 x 1–2 mL Cryogenic Vials, 4 Colors) | 12 Vials (1–2 mL) per unit | Purple, Orange, Green, Pink | 1 | 4 |
Applications
- Cryopreservation of Cells: Ideal for freezing cell lines, stem cells, PBMCs, and other sensitive samples.
- Laboratory Research: Supports consistent freezing protocols for reproducible experimental results.
- Clinical and Biotechnological Use: Used in settings requiring high recovery and viability of cells post-thaw.
Comparison with Alcohol-Based Systems
| Feature | Corning® CoolCell® | Alcohol-Based Systems |
|---|---|---|
| Freezing Rate | Consistent -1°C/minute | Variable, may be inconsistent |
| Alcohol-Free | Yes | No |
| Ease of Use | Simple, no additional steps | Requires alcohol refilling |
| Cost-Effectiveness | Reusable, no consumables | Requires regular alcohol refills |
| Environmental Impact | Minimal, eco-friendly | Generates hazardous waste |
Ordering Information
- Requires no additional consumables for operation.
- Available in multiple colors and capacities for various vial sizes (1 mL, 2 mL, 3.5–5 mL, and 10 mL).
Here’s a detailed comparison between the Corning® CoolCell® Containers and Thermo Scientific™ Mr. Frosty™ Freezing Containers for controlled-rate freezing:
| Feature | Corning® CoolCell® | Thermo Scientific™ Mr. Frosty™ |
|---|---|---|
| Cooling Rate | ~-1°C/min (with -80°C freezer) | ~-1°C/min (with isopropyl alcohol and -80°C freezer) |
| Design | Alcohol-free, uses cross-linked polyethylene foam and solid-state core. | Alcohol-based, requires 100% isopropyl alcohol. |
| Capacity | - Models for 12 to 30 vials (1–2 mL, 3.5–5 mL, 10 mL). - Color-coded options for easy differentiation. | - Models for 12 to 18 vials (1–2 mL, 3.6 mL, 4.5–5 mL). |
| Ease of Use | - Alcohol-free setup simplifies the process. - Vials are removed by inverting the container. | - Requires isopropyl alcohol preparation. - Screw-top lid prevents spills during tipping. |
| Durability | Reusable, robust foam design resistant to wear. | Durable polycarbonate construction for repeated use. |
| Cost of Use | Lower, as no alcohol is required for operation. | Higher, due to recurring costs of isopropyl alcohol. |
| Environmental Impact | Eco-friendly: alcohol-free, reducing hazardous waste. | Generates hazardous waste due to alcohol usage. |
| Space Efficiency | Compact and stackable, minimizes freezer footprint. | Compact, but requires space for alcohol storage. |
| Temperature Control | Consistent freezing profile; protects nearby frozen samples from temperature fluctuations. | Consistent freezing rate; alcohol may impact freezer environment if spilled. |
| Safety | No hazardous material handling (alcohol-free). | Requires handling of flammable isopropyl alcohol. |
| Compatibility | - Compatible with cryogenic vials (1–5 mL). - Multiple sizes for specific vial types. | - Compatible with cryogenic vials (1–5 mL). - Limited size options. |
Advantages of Corning® CoolCell®
- Alcohol-Free Design: Reduces recurring costs and eliminates flammable hazards.
- Eco-Friendly: No hazardous waste from isopropyl alcohol disposal.
- Color Options: Available in multiple colors (purple, green, orange, pink) for easy vial identification.
- Cost-Effective: Lower operational costs over time.
- Simpler Handling: No need for alcohol preparation or refilling.
Advantages of Thermo Scientific™ Mr. Frosty™
- Initial Cost: Typically lower upfront cost compared to Corning CoolCell.
- Proven Technology: Widely used in labs familiar with alcohol-based systems.
- Secure Storage: Screw-top lid prevents spills during freezing and transport.
Ideal Applications
| Use Case | Corning® CoolCell® | Thermo Scientific™ Mr. Frosty™ |
|---|---|---|
| Routine Lab Use | Cost-efficient, alcohol-free. | Suitable but incurs higher recurring costs. |
| High Throughput Freezing | FTS30 model accommodates 30 vials. | Limited to 12–18 vials per container. |
| Eco-Friendly Labs | Best choice for sustainability goals. | Less environmentally friendly. |
| Clinical Research | Offers consistent results and simplicity. | Offers consistent freezing but requires alcohol. |
| Budget-Conscious Labs | Lower long-term costs without alcohol. | Lower initial investment. |
Summary
- Corning® CoolCell® is an excellent choice for labs prioritizing eco-friendliness, long-term cost savings, and ease of use.
- Thermo Scientific™ Mr. Frosty™ is ideal for those with lower initial budgets or those already accustomed to alcohol-based freezing systems.
- Description: CoolCell® LX, exposed tops for 12 standard 1.0 mL to 2.0 mL cryogenic vials, Purple CoolCell® LX, exposed tops for 12 standard 1.0 mL to 2.0 mL cryogenic vials, Green CoolCell® LX, exposed tops for 12 standard 1.0 mL to 2.0 mL cryogenic vials, Orange CoolCell® LX, exposed tops for 12 standard 1.0 mL to 2.0 mL cryogenic vials, Pink CoolCell® LX, exposed tops for 12 standard 1.0 mL to 2.0 mL cryogenic vials (each one purple, orange, green and pink), Assorted colours, 4/pk CoolCell® FTS30, exposed tops for 30x1 ml or 2 ml cryogenic vials, Purple CoolCell® FTS30, exposed tops for 30x1 ml or 2 ml cryogenic vials, Orange CoolCell® FTS30, exposed tops for 30x1 ml or 2 ml cryogenic vials, Green CoolCell® FTS30, exposed tops for 30x1 ml or 2 ml cryogenic vials, Pink CoolCell® 5 ml LX, exposed tops for 12x3.5 mL to 5 mL cryogenic vials, Purple CoolCell® SV10, exposed tops for 6 standard 10.0 mL injectable ampules, Purple CoolCell® SV2, exposed tops for 12 standard 2.0 mL injectable ampules, Purple CoolCell®, fully covered tops, For 12 standard 1.0 mL to 2.0 mL cryogenic vials
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