Beckman Coulter™ RNAClean XP RNA and cDNA Cleanup Reagent

RNAClean XP is a high-efficiency, magnetic bead-based reagent designed for the purification and cleanup of RNA and cDNA from a wide variety of enzymatic reactions. Based on Solid Phase Reversible Immobilization (SPRI) technology, this reagent ensures the removal of salts, enzymes, unincorporated primers, and dNTPs, delivering pure RNA or cDNA suitable for sensitive downstream applications such as RT-PCR, qPCR, RNA-Seq, and in vitro transcription (IVT).

This reagent is compatible with both manual workflows and automation platforms, making it ideal for both small- and high-throughput laboratories. Certified RNase-free, RNAClean XP ensures the integrity of RNA through the entire purification process.

Key Features and Benefits

• SPRI-based magnetic bead technology for efficient purification
• Removes salts, free nucleotides, primers, and enzymes
• Compatible with automated liquid handlers and manual protocols
• Ideal for RNA-Seq library preparation, RT-PCR, and cDNA workflows
• RNase-free formulation ensures RNA integrity
• Flexible reagent volumes: 40 mL (A63987) and 450 mL (A66514)

Applications

• RNA cleanup after enzymatic reactions
• cDNA purification following reverse transcription
• IVT reaction cleanup
• Next-generation sequencing (NGS) RNA library prep
• High-throughput sample processing and automation

Technical Specifications

RNAClean XP delivers high-quality RNA and cDNA purification through a reliable bead-based cleanup system trusted across genomics, transcriptomics, and molecular biology labs. Whether preparing RNA for sequencing or cDNA for amplification, RNAClean XP ensures high purity and compatibility with sensitive downstream applications in both manual and automated workflows.