Sigma-Aldrich AmberChrom™ 1X4 chloride form, 20-50 mesh, Anion Exchange Resin

Sigma-Aldrich AmberChrom™ 1X4 is a strongly basic Type I anion exchange resin in chloride (Cl⁻) form, designed for pharmaceutical purification, environmental analysis, and industrial water treatment applications. This gel-type, polystyrene-divinylbenzene copolymer resin contains quaternary ammonium functional groups, enabling high-efficiency removal of anionic contaminants such as fluoride (F⁻), chloride (Cl⁻), sulfate (SO₄²⁻), and iodinated compounds from aqueous solutions.

AmberChrom™ 1X4 is used in fine pharmaceutical processing, chemical separations, and ion-exchange chromatography. Its high moisture content (>50%) and cross-linkage of 4% provide excellent exchange kinetics and resin stability, making it suitable for laboratory and industrial-scale applications.

Key Features & Benefits

1. Strongly Basic Type I Anion Exchange Resin
   • Removes sulfates, chlorides, fluorides, and iodinated compounds.
   • Ideal for fine pharmaceutical purification and environmental monitoring.
2. Highly Efficient & Chemically Stable
   • Operates effectively over a wide pH range (0-14).
   • Cross-linked at 4% for enhanced ion-exchange efficiency and fast kinetics.
3. Optimized for Industrial & Research Applications
   • Used in pharmaceutical production, chemical separations, and capillary electrophoresis.
   • Complies with FDA Food Additive Regulation 21 CFR 173.25, ensuring safety in food-grade applications.
4. Versatile in Water Purification & Ion-Exchange Separation
   • Applied in deionization, wastewater treatment, and removal of residual fluoride and halides.
   • Used in nuclear magnetic resonance (NMR) analysis of iodinated contrast media.
5. Regenerable & Cost-Effective
   • Easily regenerated using sodium chloride (NaCl) or hydroxide (NaOH) solutions.
   • Long operational life with multiple regeneration cycles, reducing costs.

Product Specifications

Use Cases & Applications

1. Pharmaceutical Processing & Fine Chemical Purification

• Pharmaceutical Ingredient Purification:
  • Removes undesirable anions from drug formulations.
  • Used in chromatographic separation of pharmaceutical compounds.
• Ion-Exchange Resin for Capillary Electrophoresis & NMR Analysis:
  • Used in characterization of iodinated contrast media using ¹¹B NMR and electrophoresis.
  • Facilitates separation of fluoride-containing compounds in analytical research.

2. Industrial Water Treatment & Deionization

• Removal of Fluoride & Halides from Process Water:
  • Applied in wastewater treatment for fluoride removal.
  • Used in industrial effluent processing to eliminate halides and sulfates.
• Deionization & Water Softening:
  • Works in combination with cation exchange resins for high-purity water production.
  • Improves water quality in food processing and power generation.

3. Environmental & Wastewater Treatment

• Heavy Metal & Contaminant Removal from Wastewater:
  • Binds and removes toxic anions such as chromates, arsenates, and sulfates.
  • Used in environmental cleanup and compliance with discharge regulations.
• Ion-Exchange Resin for Environmental Analysis:
  • Applied in analytical testing for water contaminants.
  • Ensures high-resolution separation of ionic compounds in chromatography.

4. Food & Beverage Industry Applications

• FDA-Approved Resin for Food Processing:
  • Meets FDA 21 CFR 173.25 standards for food-grade water treatment.
  • Used in purification of food and beverage processing water.
• Removal of Unwanted Anions from Processed Liquids:
  • Eliminates off-flavor-causing ions from beverages.
  • Maintains product quality in the brewing and dairy industries.

5. Chemical Processing & Catalysis

• Ion Exchange in Organic Synthesis:
  • Supports catalytic reactions requiring anion exchange functionality.
  • Used in polymerization and chemical separation applications.
• pH Adjustment & Ionic Control in Chemical Reactions:
  • Maintains stable reaction conditions by controlling anionic concentrations.
  • Enhances efficiency in chemical and petrochemical production.

Regeneration & Maintenance

• Regenerate using NaCl (sodium chloride) or NaOH (sodium hydroxide) solution.
• Flush with deionized water after regeneration to remove excess chloride.
• Store in a moist condition to prevent drying and loss of ion exchange capacity.

Storage & Handling Instructions

• Storage Conditions:
  • Store in a sealed container at room temperature (15-25°C).
  • Keep in a cool, dry environment away from direct sunlight.
• Handling Precautions:
  • Use protective gloves, eyewear, and lab coats during handling.
  • Ensure proper ventilation when working with large resin volumes.
• Disposal Guidelines:
  • Follow local environmental regulations for resin disposal.
  • Used resin should be disposed of as non-hazardous waste or regenerated if applicable.

Why Choose Sigma-Aldrich AmberChrom™ 1X4?

✅ Strong base anion exchange resin for industrial and laboratory applications

✅ Removes sulfates, halides, fluorides, and iodinated compounds efficiently

✅ Meets FDA regulations for food-grade water purification

✅ Regenerable for cost-effective, long-term operation

✅ Versatile applications in pharmaceuticals, water treatment, and chromatography

AmberChrom™ 1X4 is a high-performance anion exchange resin designed for water purification, pharmaceutical processing, and industrial deionization, making it a trusted solution for high-purity applications.