MALDI Biotyper® IVD Matrix HCCA-portioned, 2.5mg per tube

The Bruker MALDI Biotyper® IVD Matrix HCCA-portioned is a high-purity α-cyano-4-hydroxycinnamic acid (HCCA) matrix designed for use in MALDI-TOF mass spectrometry microbial identification systems, specifically the MALDI Biotyper IVD. Each tube contains 2.5 mg of pre-portioned HCCA for convenience and accuracy in preparation. This matrix is part of Bruker’s standardized reagents and kits that enable precise microbial identification and ensures compliance with in vitro diagnostic (IVD) standards.

• Key Features:
  1. High Purity: Ensures minimal background noise in mass spectrometry, yielding cleaner spectra.
  2. Pre-Portioned: Precisely measured for consistent results, minimizing preparation errors.
  3. IVD-Compliant: Certified for use in clinical diagnostics under strict regulatory standards.
  4. Convenience: Each pack contains 10 tubes, reducing the risk of contamination during frequent use.
  5. Optimized for MALDI-TOF MS: Formulated specifically for use with the Bruker MALDI Biotyper systems.

Applications

1. Clinical Microbiology:
   • Identification of bacteria, yeast, and other pathogens directly from cultured samples.
   • Supports rapid and accurate diagnosis, aiding antimicrobial stewardship by informing targeted therapy.
2. Pharmaceutical Quality Control:
   • Detection of microbial contamination in production environments or products.
   • Ensures compliance with Good Manufacturing Practices (GMP).
3. Food and Beverage Microbiology:
   • Identifies spoilage organisms and pathogens in raw materials, finished goods, and production lines.
   • Enhances food safety and regulatory compliance.
4. Environmental Microbiology:
   • Analyzing water or soil samples for the presence of microbial communities.
   • Useful in monitoring bioremediation processes or environmental health.
5. Veterinary Diagnostics:
   • Pathogen identification for veterinary infections, assisting in treatment decisions for animals.
6. Academic and Industrial Research:
   • Characterization of microbial strains for research or biotechnological applications.
   • Discovery of novel microbial taxa through high-resolution mass spectrometry.

Use Cases

1. Rapid Pathogen Identification in Hospitals:
   • Using the matrix with MALDI-TOF MS, laboratories can quickly identify infectious agents like Escherichia coli, Staphylococcus aureus, or Candida albicans, reducing diagnostic turnaround time.
2. Outbreak Investigations:
   • Enables fast identification of bacterial species during disease outbreaks, ensuring appropriate control measures.
3. Antibiotic Resistance Studies:
   • Identifying resistant organisms by integrating microbial identification with antimicrobial susceptibility data.
4. Quality Assurance in Biopharmaceuticals:
   • Detection and profiling of biopharmaceutical contaminants or production strains.
5. Validation of MALDI Systems:
   • Routine calibration and quality control of MALDI-TOF MS instruments to maintain analytical accuracy.

Storage and Handling

• Store at controlled room temperature as specified by Bruker’s guidelines.
• Handle in clean conditions to prevent contamination of the matrix or working area.

Product Specifications

• Matrix: α-Cyano-4-Hydroxycinnamic Acid (HCCA).
• Concentration per Tube: 2.5 mg.
• Packaging: 10 tubes per pack.
• Intended Use: For in vitro diagnostic applications, certified for MALDI-TOF MS systems.

This product is a crucial reagent in MALDI-TOF-based workflows, offering precision and reliability for various microbial identification and diagnostic applications.