Autobio Blood Culture Bottles

The Autobio Blood Culture Bottles are designed for automated detection of bacteremia and fungemia using the Autobio BC series Automated Blood Culture Systems.

They provide an optimal environment for the growth and detection of microorganisms that invade the bloodstream, including bacteria, fungi, and mycobacteria.

Each bottle type contains a specialized nutrient formulation optimized for aerobic, anaerobic, fungal, and mycobacterial organisms, ensuring high recovery rates even from low microbial loads.

The culture bottles integrate seamlessly with Autobio BC60 and BC120 instruments, supporting continuous monitoring, antibiotic neutralization, and early detection of positive cultures.

Clinical Background

Blood is normally a sterile environment, but infection with bacteria or fungi can lead to bacteremia or fungemia—severe bloodstream infections that can progress to sepsis or septic shock, conditions associated with high mortality rates.

Early and accurate detection of microorganisms through blood culture is essential for effective diagnosis, targeted antimicrobial therapy, and improved patient outcomes.

Available Bottle Types

Key Features

1. High Sensitivity and Recovery Rate: Optimized culture medium for fastidious and slow-growing microorganisms.
2. Antibiotic Neutralization: Contains macroporous resins and cation exchange agents that inactivate residual antibiotics, ensuring better detection rates.
3. V and X Growth Factors: Enhance recovery of fastidious bacteria (e.g., Haemophilus and Neisseria).
4. Vacuum-Based Quantitative Sampling: Ensures accurate and safe blood collection.
5. Double Barcode Tracking: Enables full traceability from collection to reporting.
6. High-Strength Plastic Design: Prevents breakage and ensures biosafety during handling and incubation.
7. Compatibility: Fully compatible with Autobio BC60/BC120 systems and other imported blood culture analyzers.
8. Fast Detection: Positive results can be reported in as little as 3 hours under optimized conditions.

Specifications

Quality Control

Performance validation performed using ATCC® and CMCC® reference strains, confirming positive detection under standardized conditions:

• Staphylococcus aureus ATCC 25923
• Escherichia coli ATCC 25922
• Candida albicans ATCC 10231
• Clostridium perfringens ATCC 13124

Applications

• Clinical Diagnostics: Detection of bloodstream infections (BSI), sepsis, and bacteremia.
• Hospital Infection Control: Monitoring catheter-associated bloodstream infections.
• Public Health and Research: Epidemiological tracking of bacterial and fungal bloodstream infections.
• Pharmaceutical Microbiology: Validation of sterile manufacturing and contamination testing.
• Mycobacteriology: Isolation and culture of Mycobacterium tuberculosis and related species.

Unique Advantages

• Early positive detection in as little as 3 hours.
• Enhanced pathogen recovery due to optimized media and growth factors.
• Excellent antibiotic neutralization ensures accurate detection.
• High bio-safety design with durable materials and secure seals.
• Full traceability with dual barcoding system.
• Inter-system compatibility allows use across various analyzers.

The Autobio Blood Culture Bottles are engineered for high-performance microbial detection, ensuring fast, accurate, and reliable results in the diagnosis of bloodstream infections.

With enhanced growth media, antibiotic neutralization, and integrated tracking, they are ideal for clinical microbiology, infection control, and research laboratories.

These bottles deliver maximum reliability and biosafety, providing optimal support for the Autobio BC Series Blood Culture Systems.